News

United Spinal Association Demands Wheelchair Accessible Taxicabs in DC for Those With ALS, Other Spinal Conditions

The national nonprofit United Spinal Association is advocating along with the Washington DC Taxicab Commission (DCTC) for the implementation of the DC Taxicab Service Improvement Amendment Act of 2012’s regulations and an increase in taxis able to carry wheelchairs. The implementation of the rule may impact the lives of people suffering from…

Clinical Trial Will Explore Genetic identification of Familial and Sporadic Amyotrophic Lateral Sclerosis

Investigators at the Northwestern University Feinberg School of Medicine are currently enrolling participants for a clinical trial (ClinicalTrials.gov Identifier: NCT00821132), that aims to identify genes that increase risk for sporadic Amyotrophic Lateral Sclerosis (ALS) or cause inherited ALS. The study, entitled “Identification of Genes Causing Familial ALS or Increasing Risk…

OptiKira To Develop Cell-Protective Therapeutics For Unfolded Protein Response

BioMotiv is a drug advancement accelerator associated with The Harrington Project, the University of California San Francisco (UCSF), and University of Washington, Seattle working on breakthrough discoveries and new therapeutics that have the potential to address unmet clinical needs. Recently, the accelerator announced the creation of a platform company, OptiKira, that will…

Recent Genetics Research May Hold Clues to New ALS Treatments

Dr. Nancy Bonini A recent editorial published in the journal Neurology highlights the existing scope of clinical knowledge concerning genetic susceptibility that makes individuals prone to developing amyotrophic lateral sclerosis (ALS). The editorial content was based on a thorough…

New Experimental Model Uses Astrocytes to Test Therapies for ALS

A research team from the University of Wisconsin-Madison Waisman Center led by Su Chun Zhang, established a simple model in mice to investigate the role of human astrocytes in neurologic diseases such as Amyotrophic Lateral Sclerosis (ALS), Rett Syndrome and Huntington’s disease. The study entitled…

Genervon’s One-Patient ALS Drug Study Reveals Promising Results

Biopharmaceutical company Genervon recently reported observing improvements in a 46-year-old-man with advanced amyotrophic lateral sclerosis (ALS) taking the Company’s drug candidate GM604. The patient showed increased speech, swallowing and suction capabilities after a 12-week treatment. The drug, which has yet to be approved by the…

ALS Tissue-Engineered Skin May Hold Key to Early Diagnoses

A recent study, titled, “Early detection of structural abnormalities and cytoplasmic accumulation of TDP-43 in tissue-engineered skins derived from ALS patients,” published in the journal, Acta Neuropathologica Communications, details the creation of a novel tissue-engineered skin model for amyotrophic lateral sclerosis (ALS). ALS is a progressive…