disease progression

June 5, 2019June 5, 2019

Electronic App to Monitor Dietary Intake May Benefit ALS Patients, Trial Data Suggest

News

A diet monitoring app can help amyotrophic lateral sclerosis (ALS) patients to manage their calorie intake in order to maintain or even improve their weight, and achieve better outcomes, ... Read more

May 30, 2019May 30, 2019

Histamine-Related Genes May Become Biomarkers and Therapeutic Targets for ALS, Mouse Study Suggests

News

Histamine-related genes are promising disease biomarkers and therapeutic targets to slow amyotrophic lateral sclerosis (ALS) progression, a mouse study suggests. The study, “Histaminergic transmission slows progression of amyotrophic lateral ... Read more

May 9, 2019May 9, 2019

#AANAM – Reldesemtiv Reduces Lung Function Decline and ALS Progression, Phase 2 Trial Shows

News

Reldesemtiv (formerly known as CK-2127107) reduces lung function decline and overall disease progression, without significant adverse events, in people with amyotrophic lateral sclerosis (ALS), a Phase 2 trial shows. ... Read more

May 7, 2019May 7, 2019

#AANAM – Vitamin D Activator is Muscle Biomarker in ALS, May Indicate Clinical Progression, Study Contends

News

A vitamin D activator molecule known as CYP27B1 is a biomarker of muscle alterations in patients with amytrophic lateral sclerosis (ALS) and may be a marker of clinical progression ... Read more

April 10, 2019May 15, 2019

Specific Molecular Patterns Could be a Strong Marker for ALS Progression and Prognosis, Study Contends

News

The patterns of methylation in arginine residues circulating in the cerebrospinal fluid — the liquid that circulates in the brain and spinal cord — could be a strong indicator of ... Read more

February 25, 2019February 25, 2019

Nerve Injury May Trigger Onset, Progression of ALS Symptoms, Rat Study Suggests

News

Small nerve injury may be the trigger for early manifestation or faster progression of amyotrophic lateral sclerosis (ALS) motor symptoms in the presence of disease-associated genetic contributing factors, a ... Read more

January 11, 2019January 11, 2019

Disease Progression Has Significant Effect on Quality of Life of ALS Patients, Study Says

News

In addition to symptoms of depression, disease progression is one of the strongest influences on health-related quality of life in amyotrophic lateral sclerosis (ALS) patients, a study reports. According to the study, ... Read more

January 10, 2019January 10, 2019

CuATSM Therapy May Slow ALS Progression, Improving Cognition and Respiration in Patients, Phase 1 Trial Shows

News

CuATSM, one of the lead investigational therapies of Collaborative Medicinal Development (CMD), may slow disease progression and improve the respiratory and cognitive function of patients with amyotrophic lateral sclerosis ... Read more

October 3, 2018

BioElectron’s EPI-589 Shows Positive Results in ALS Patients in Phase 2a Trial

News

Investigational compound EPI-589 was found to be safe and well-tolerated, improved biomarkers of neuroinflammation, and showed signs of slowing disease progression in amyotrophic lateral sclerosis (ALS) patients, according to a ... Read more

September 21, 2018September 21, 2018

Parkinson’s Therapy Azilect Added to Rilutek May Delay Fast-progressing ALS, Phase 2 Trial Shows

News

Adding Azilect (rasagiline) — a medication already approved to treat Parkinson’s disease — to Rilutek (riluzole) may be able to slow the advancement of fast-progressing amyotrophic lateral sclerosis (ALS), a Phase ... Read more

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