disease progression

September 20, 2017

Cell Cleaning Mechanism Has Dual Role in ALS, Study Finds

News

A mechanism that cells normally use to keep them healthy was found to have a dual role in amyotrophic lateral sclerosis (ALS). While the process, called autophagy, delays disease progression ... Read more

August 30, 2017August 30, 2017

Researchers Identify Novel Genes that Regulate Muscle Stimulation and Regeneration in ALS

News

Levels of some microRNAs (MIRs) regulating re-innervation and muscle regeneration among amyotrophic lateral sclerosis (ALS) patients, while others are lower, an Italian study has found. These molecules help distinguish ... Read more

March 28, 2017

Urine Levels of Protein p75ECD May Help Diagnose, Monitor ALS, Study Reports

News

Urine levels of a protein component known as p75ECD may be a valuable biomarker for diagnosing and monitoring the progression of amyotrophic lateral sclerosis (ALS), according to a study. The ... Read more

March 16, 2017March 16, 2017

European Study Reviews Importance of Population-based Registers of ALS Patients

News

A recent review highlights the importance of population-based registers of amyotrophic lateral sclerosis (ALS) in Europe, which for more than 20 years have helped scientists understand the disease’s incidence, prevalence, characterization and genetics, ... Read more

February 10, 2017February 10, 2017

Researchers Develop New Molecule, 123C4, with Possibility to Treat ALS

News

Researchers have developed a molecule called 123C4 that targets the EphA4 receptor, which is known to contribute to the development of amyotrophic lateral sclerosis (ALS), according to a new study. ... Read more

January 18, 2017January 18, 2017

Cholesterol-Related Molecule May Be Linked to ALS Progression

News

High levels of 25-hydroxycholesterol, a cholesterol-related molecule, may trigger neuronal death and accelerate amyotrophic lateral sclerosis (ALS) progression, according to a new study. The finding could lead to new ... Read more

December 20, 2016December 20, 2016

Brains of ALS Patients ‘Wired’ Differently and That’s Evident in Disability, Study Says

News

Patients with amyotrophic lateral sclerosis (ALS) have a different functional brain network than healthy individuals, and that difference appears to be strongly associated with disability, according to new research. This finding ... Read more

October 6, 2016October 20, 2016

Antibodies Circulating in Blood May Serve as Biomarker for ALS, Disease Severity

News

The presence of a certain type of proteins of the immune system in the blood may serve as a reliable biomarker for the diagnosis of amyotrophic lateral sclerosis (ALS), ... Read more

September 23, 2016

Smoking Speeds Progression of ALS and Reduces Survival Longevity

News

Cigarette smoking may speed progression of amyotrophic lateral sclerosis (ALS) and reduce survival in patients with the disease, according to a new collaborative study from Italian universities and research institutes. The ... Read more

July 1, 2016July 1, 2016

ALS Patients May Safely Undergo Stem Cell Transplants, Study Reports

amyotrophic lateral sclerosis (ALS), News

Transplanting human stem cells into the spinal cord of people with amyotrophic lateral sclerosis (ALS) may be safely accomplished, according to the results of a Phase 2 clinical trial. ... Read more