disease progression

October 3, 2018

BioElectron’s EPI-589 Shows Positive Results in ALS Patients in Phase 2a Trial

News

Investigational compound EPI-589 was found to be safe and well-tolerated, improved biomarkers of neuroinflammation, and showed signs of slowing disease progression in amyotrophic lateral sclerosis (ALS) patients, according to a ... Read more

September 21, 2018September 21, 2018

Parkinson’s Therapy Azilect Added to Rilutek May Delay Fast-progressing ALS, Phase 2 Trial Shows

News

Adding Azilect (rasagiline) — a medication already approved to treat Parkinson’s disease — to Rilutek (riluzole) may be able to slow the advancement of fast-progressing amyotrophic lateral sclerosis (ALS), a Phase ... Read more

September 14, 2018September 14, 2018

Problems with Behavior and Thinking Skills Evident in ALS Patients and Progress with Disease, UK Study Says

News

Amyotrophic lateral sclerosis’ toll on the thinking abilities and behavior of patients is as progressive and damaging as the disease’s physical toll, researchers in the U.K. report, with ALS-specific cognitive ... Read more

August 28, 2018August 28, 2018

Combination of Imaging, Biomarkers Offers Better Assessment of ALS Patients, Study Finds

News

Combining structural brain imaging with molecular and clinical biomarkers allows for a detailed assessment of a patient’s clinical state, regardless of age and amyotrophic lateral sclerosis progression, a new study ... Read more

August 8, 2018August 6, 2018

Let’s Get Physical: The ALS Exercise Debate

Columns, Notes From the ALS Front - a Column by Rick Jobus

“Use it, or lose it.” That was the motivational summary statement during my first post-ALS diagnosis physical therapy (PT) session. As my condition’s horrific prognosis continued percolating in my ... Read more

June 7, 2018June 7, 2018

Infusing Treg Immune Cells Has Potential to Slow ALS, Small Study Suggests

News

Results from a Phase 1 clinical trial reveal that giving patients infusions of a specialized immune cell may be a viable option to safely slow the progression of amyotrophic ... Read more

May 21, 2018May 21, 2018

Protein That Helps to Regulate Innate Immune System Seen to Slow ALS Progression in Early Study in Mice

News

The protein TRIF can prevent resident immune cells of the brain from activating abnormally and slow the progression of amyotrophic lateral sclerosis (ALS), researchers in Japan working in a mouse model ... Read more

April 20, 2018April 20, 2018

#AAN2018 – H.P. Acthar Gel Shows Promise as Therapy to Delay Progression of ALS

News

H.P. Acthar Gel, an experimental injectable therapy, may help delay progression of amyotrophic lateral sclerosis (ALS), a new analysis reveals. The data is scheduled to be presented at the ... Read more

April 13, 2018April 13, 2018

New Study Reveals Two Genes Associated with High Risk for ALS

News

Genetic mutations in two previously unrecognized genes, the microtubule-associated protein tau (MAPT) and BNIP1 genes, are associated with elevated risk for amyotrophic lateral sclerosis (ALS). The study with that ... Read more

April 10, 2018April 10, 2018

Rilutek Prolongs Survival of ALS Patients in Later Stages, Study Shows

News

Rilutek (riluzole) extends survival of patients with amyotrophic lateral sclerosis (ALS) who are at advanced stages of the disease, rather than preventing disease progression is early stages. Those findings ... Read more

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