disease progression

April 10, 2019April 10, 2019

Specific Molecular Patterns Could be a Strong Marker for ALS Progression and Prognosis, Study Contends

News

The patterns of methylation in arginine residues circulating in the cerebrospinal fluid — the liquid that circulates in the brain and spinal cord — could be a strong indicator of ... Read more

February 25, 2019February 25, 2019

Nerve Injury May Trigger Onset, Progression of ALS Symptoms, Rat Study Suggests

News

Small nerve injury may be the trigger for early manifestation or faster progression of amyotrophic lateral sclerosis (ALS) motor symptoms in the presence of disease-associated genetic contributing factors, a ... Read more

January 11, 2019January 11, 2019

Disease Progression Has Significant Effect on Quality of Life of ALS Patients, Study Says

News

In addition to symptoms of depression, disease progression is one of the strongest influences on health-related quality of life in amyotrophic lateral sclerosis (ALS) patients, a study reports. According to the study, ... Read more

January 10, 2019January 10, 2019

CuATSM Therapy May Slow ALS Progression, Improving Cognition and Respiration in Patients, Phase 1 Trial Shows

News

CuATSM, one of the lead investigational therapies of Collaborative Medicinal Development (CMD), may slow disease progression and improve the respiratory and cognitive function of patients with amyotrophic lateral sclerosis ... Read more

October 3, 2018

BioElectron’s EPI-589 Shows Positive Results in ALS Patients in Phase 2a Trial

News

Investigational compound EPI-589 was found to be safe and well-tolerated, improved biomarkers of neuroinflammation, and showed signs of slowing disease progression in amyotrophic lateral sclerosis (ALS) patients, according to a ... Read more

September 21, 2018September 21, 2018

Parkinson’s Therapy Azilect Added to Rilutek May Delay Fast-progressing ALS, Phase 2 Trial Shows

News

Adding Azilect (rasagiline) — a medication already approved to treat Parkinson’s disease — to Rilutek (riluzole) may be able to slow the advancement of fast-progressing amyotrophic lateral sclerosis (ALS), a Phase ... Read more

September 14, 2018September 14, 2018

Problems with Behavior and Thinking Skills Evident in ALS Patients and Progress with Disease, UK Study Says

News

Amyotrophic lateral sclerosis’ toll on the thinking abilities and behavior of patients is as progressive and damaging as the disease’s physical toll, researchers in the U.K. report, with ALS-specific cognitive ... Read more

August 28, 2018August 28, 2018

Combination of Imaging, Biomarkers Offers Better Assessment of ALS Patients, Study Finds

News

Combining structural brain imaging with molecular and clinical biomarkers allows for a detailed assessment of a patient’s clinical state, regardless of age and amyotrophic lateral sclerosis progression, a new study ... Read more

August 8, 2018August 6, 2018

Let’s Get Physical: The ALS Exercise Debate

Columns, Notes From the ALS Front - a Column by Rick Jobus

“Use it, or lose it.” That was the motivational summary statement during my first post-ALS diagnosis physical therapy (PT) session. As my condition’s horrific prognosis continued percolating in my ... Read more

June 7, 2018June 7, 2018

Infusing Treg Immune Cells Has Potential to Slow ALS, Small Study Suggests

News

Results from a Phase 1 clinical trial reveal that giving patients infusions of a specialized immune cell may be a viable option to safely slow the progression of amyotrophic ... Read more

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