First to answer your question yes . Ayahuasca no DMt ,Mushrooms ,yes. I don’t know about micro dosing if 1/10000 of a gram is micro well sure. It certainly has helped me deal with a difficult situation. I would also point out that evidence suggests many of these substances are neuroprotective and highly effective at treating depression. If you are familiar with using these things by all means go for it. If you are not be sure to be in a safe place with people you trust. Music may be helpful. The state of your mind has an effect on any disease progression. These substances can be powerful tools . I would avoid Ayahuasca as it involves the use of maoi inhibitors. As the name suggests harmaline and harmine are not always safe with other foods and drugs. Mushrooms ,DMT , and Lsd have few interactions are not addictive have been used by many people and if care is taken in choosing where when and with whom they are used other than in cases of schizophrenia are quite safe.  Love and good wishes.