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Klaus68

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@kcharisse68

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    Klaus68 replied to the topic Is non-familial ALS a genetic disease? in the forum Diagnosis​ ​Information​ ​and​ ​General​ ​Questions 2 months, 3 weeks ago

    Michael, difficult to answer with a clear yes or no.  In familiar ALS we have the genes e.g  C9orf72, FUS and SOD1 with clear causalities in ALS cause by damaging motor neurons (MN) mostly triggering the mislocation of the hallmark ALS protein TDP-43 from the nucleus to cytosol and generating TDP-43 deposits.  Since TDP is regulating its gene ex…[Read more]

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    Klaus68 replied to the topic Relyvrio in the forum Diagnosis​ ​Information​ ​and​ ​General​ ​Questions 2 months, 3 weeks ago

    Very good point about the antiacids. Aluminium and magnesium salts of phenylbutyrate might be very insoluble. They often are.
    Suzanne, are you taking any medication for your lack of gallbladder. usually this is the case. It might make sense to discuss with your PCP. Eventually you can reduce this medication now and see if the diarrhea gets better.…[Read more]

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    Klaus68 replied to the topic Relyvrio in the forum Diagnosis​ ​Information​ ​and​ ​General​ ​Questions 2 months, 3 weeks ago

    I have been on Relyvrio (BTW terrible name choice IMO) since about a month. (I am also on Radicava oral and Riluzole since my diagnosis in July 2022)) . I have not noticed any side effect from Relyvrio. I do combat the truly terrible taste with chasing it with a small glass of LEAP 2befit (orange) in the evening and in the morning with coffee…[Read more]

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    Amanda and Profile picture of Klaus68Klaus68 are now friends 3 months, 2 weeks ago

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    Klaus68 became a registered member 7 months, 1 week ago

    • Profile picture of Dagmar Munn
      Dagmar Munn replied 7 months, 1 week ago

      Hello Klaus68,

      Welcome to the forum! I am one of the forum moderators and a person living with ALS: I was diagnosed in 2010.

      If there is anything specific you would like to see discussed on the forum, feel free to post a new topic in any of our forums or jump in on an existing topic. You can also search for past topics or discussions by typing a…[Read more]

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      Amanda replied 7 months, 1 week ago

      Hello Klaus68,
      Welcome to the ALS forum. I’m Amanda, one of the co-moderators of the forum. ALS is a dreadful disease and we all want to understand it better, and find a cure!!

      We are happy you have joined our online community. You will find that the ALS forum is made up of people with different associations with ALS. My family has an extensive h…[Read more]

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    Klaus68's profile was updated 7 months, 1 week ago

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