NEK1 Gene Variants Increase Odds of Developing ALS, Study Finds
Genetic variants of the NEK1 gene that cause the coded protein to lose its function seem to increase the…
Articles by Inês Martins, PhD
Tamoxifen Shows Modest Effects in ALS Patients, Phase 1/2 Trial Finds
A cancer treatment called tamoxifen, which previously showed promise in preclinical studies for the treatment of amyotrophic lateral…
Teeth of ALS Patients Show Odd Metabolism of Metals in Childhood
The teeth of people with amyotrophic lateral sclerosis (ALS) show their bodies metabolize metals — from chromium to zinc…
RESCUE-ALS Trial Enrolls More Than Half of Patients Ahead of Schedule
The Phase 2 clinical trial investigating Clene Nanomedicine‘s CNM-Au8 as a potentially disease-modifying…
Arimoclomol Earns FDA’s Fast Track Status for ALS
The U.S. Food and Drug Administration (FDA) has given fast track designation…
High Creatinine Kinase Levels Predict Slower Progression in ALS, Study Finds
Levels of creatinine kinase — a marker of muscle damage — are elevated in most amyotrophic lateral sclerosis (ALS) patients…
Gut Microbiota Affects Inflammation and Lifespan in ALS, Mouse Study Shows
Changing the composition of bacteria in the gut using antibiotics or fecal transplants may help prevent or reduce the severity…
Cerebrospinal Fluid May Transport ALS Toxins, Mouse Study Suggests
The clear, colorless liquid that fills and surrounds the brain and spinal cord may spread toxic protein aggregates from one…
Neurotoxin of Blue-Green Algal Blooms May Raise Risk of ALS
Exposure to a neurotoxic molecule produced by blue-green algae seems to raise a person’s odds of developing amyotrophic…
Rare Variants in TET2 Gene May Double Person’s Risk of ALS, Similar Ills
Rare variations in the TET2 gene seem to double a person’s risk of multiple neurodegenerative diseases, including amyotrophic…