BL-001, targeting gut microbes, found safe in healthy volunteers
BL-001, an investigational gut-targeted therapy being developed for people with amyotrophic lateral sclerosis (ALS) and Dravet syndrome, was found…
Articles by Lindsey Shapiro, PhD
Diarrhea a barrier to using common ALS medication: Surveys
Note: This story was updated Aug. 22, 2023, to correct there are four ALS approved therapies widely available in the…
Genetic factors influencing ALS survival identified in Japanese study
Researchers have identified new genetic variants that might influence survival among sporadic amyotrophic lateral sclerosis (ALS) patients in Japan.
Starting noninvasive ventilation sooner may yield survival benefit
An earlier start to noninvasive ventilation (NIV) could help to improve respiratory function and prolong survival for people with…
Intranasal formulation helps edaravone reach brain: Early study
An into-the-nose (intranasal) formulation of edaravone — the active ingredient in the amyotrophic lateral sclerosis (ALS) medication Radicava…
Amylyx agrees to deal for Albrioza reimbursement in Canada for ALS
Albrioza, the approved treatment for amyotrophic lateral sclerosis (ALS) formerly known as AMX0035, is one giant step closer to…
Parkinson’s therapy ropinirole may slow ALS progression: Trial data
Early treatment with ropinirole, a medication used to treat Parkinson’s disease, may slow disease progression in amyotrophic lateral…
KIF5A mutations, age may drive neurodegeneration in ALS: Study
Mutations in the KIF5AÂ gene, associated with some cases of amyotrophic lateral sclerosis (ALS), may lead to impairments in motor…
Locanabio’s investigational therapy shows promise for C9ORF72-associated ALS
Locanabio‘s investigational therapy significantly reduced the buildup of toxic RNA molecules in amyotrophic lateral sclerosis (ALS) patient cells…
Development of WVE-004 to cease after Phase 1/2 trial failure
WVE-004, Wave Life Sciences‘ investigational treatment for amyotrophic lateral sclerosis (ALS), significantly reduces toxic proteins associated with C9orf72 genetic mutations,…