Cell Transport Mechanism May Play Role in ALS Patients’ Nerve Cell Toxicity, Study Finds
A cell transport mechanism called endocytosis may be flawed in people with amyotrophic lateral sclerosis, a study reports. The flaw…
Articles by Magdalena Kegel
Ethical Factors Should Be at Core of Radicava Treatment Discussions, Researchers Argue
When discussing potential Radicava (edaravone) treatment with amyotrophic lateral sclerosis (ALS) patients, physicians need to take great care in…
Cell Stress Unleashes Downward Spiral of Toxic Protein Production in ALS
Cell stress, such as a viral infection, may trigger the production of faulty proteins from the C9orf72 gene, a leading…
Gene Editing Shows Promise in Treating Familial ALS, Mouse Study Suggests
Gene editing may be a viable tool to slow disease-causing processes in amyotrophic lateral sclerosis (ALS) caused…
Wave Life Sciences Therapy Reduces Levels of ALS Markers, Animal Studies Show
The Wave Life Sciences therapy WVE-3972-01 reduced markers of the form of ALS that scientists believe stems from a gene mutation,…
Stem Cell Treatment Targeting Spinal Cord Won’t Slow ALS, Researchers Say
Using stem cell treatments to protect motor neurons is not enough to prevent the loss of nerve-muscle connections and disease…
First Trial of Potential ALS Gene Therapy VM202 Shows Treatment’s Safety
The investigational gene therapy VM202, developed by VM BioPharma and intended for the treatment of amyotrophic lateral sclerosis (ALS), has been…
British Mitochondria Study Could Provide New Approaches to Treating ALS
Researchers at University of Exeter Medical School in the United Kingdom have started an ambitious project to investigate how…
C9ORF72 Mutations Limit ALS Patients’ Ability to Use Communications Devices, Study Suggests
Mutations in the C9ORF72 gene of people with amyotrophic lateral sclerosis (ALS) might make it more difficult for them to…
ALS Mutation Kills Nerve Cells by Preventing Protein Clumps from Breaking Apart, Study Reports
Researchers have discovered a new way by which a gene mutation can kill neurons in people with ALS and a…