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Everyone,
You can learn everything about Ibudilast by studying the text at https://endals.altervista.org/#ibudilast .Note the key statement near the end: “Within a subgroup of 34 Early-Stage patients, 11 (32%) experienced stable disease or improvement, which is an astonishing achievement if accurate. Each of the 11 is represented by a red line in the graph below, which comes from this very detailed 2018 trial report (a link to the report is given).
“After 3 elapsed months each of the 11 patients remained either stable (the line becomes horizontal) or improved (the line slopes upward). The remaining 22 patients (68% of the 34), represented by blue lines, continued to decline, but some less rapidly than others.”If true, this is exceedingly important, because NO OTHER drug offers stability or improvement – all others attempt to REDUCE THE RATE of decline. So, Ibudilast may be hopeful, especially for those with early stage disease.
The Japanese pharmacy and the drug dosage are given. It would be risky to buy from Europe. Such a lengthy distribution trail (Japan to Europe to USA) offers too many opportunities for a counterfeit drug to be introduced. The Japanese pharmacy, which is linked in the article, is located in the same city as the manufacturer’s research center, making counterfeit substitution unlikely.
Yusuf