People who sustain a traumatic brain injury (TBI) are more likely to die within two years from amyotrophic lateral sclerosis (ALS), according to a new analysis. But the association may reflect an early manifestation of the disease, rather than a cause. Researchers said a phenomenon called reserve causation may…
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My husband, Todd, and I recently finished watching the NBC series “The Good Place,” a comedy that explores some of life’s big questions about meaning. In the season three finale, the character Eleanor Shellstrop searches for the answer that will make everything make sense as she tries to…
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Adding a blood test that measures nerve damage or a test of brain activity to standard diagnostic criteria may help doctors diagnose amyotrophic lateral sclerosis (ALS) more accurately, a study suggests. Researchers found that incorporating either blood levels of neurofilament light chain (NfL), a biomarker of nerve cell damage, or…
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Treatment with a novel one-time gene therapy improved motor function and extended survival in a mouse model of amyotrophic lateral sclerosis (ALS) driven by mutations in the SOD1 gene, according to researchers from the University of Massachusetts Chan Medical School. The results, the team noted,…
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A panel of 19 blood proteins may help estimate when symptoms of amyotrophic lateral sclerosis (ALS) will emerge in people who carry disease-associated genetic variants, a new study suggests. When the model was tested using data from carriers whose symptom-onset dates were known, its estimates differed from the actual timing…
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For people serving in the U.S. armed forces, the risk of developing amyotrophic lateral sclerosis (ALS) varies by military branch and rank, a study suggested. The study found the risk of ALS is lower among people in the Marines or Army than among those who served in the Coast…
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Mutations in the NEK1 gene — a major genetic cause of amyotrophic lateral sclerosis (ALS) — can disrupt the molecular machinery that cells normally rely on to make new proteins, according to a new study. The results shed new light on the molecular mechanisms by which certain mutations can contribute…
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Becoming educated and informed about ALS is a good first step. Here you’ll find general information about the disease, including diagnosis, symptoms, and causes.
It helps to know others have been where you are now. Here’s a collection of our columnists’ words of wisdom to help you along on your ALS journey.
There is no cure for ALS yet, but here you can find more information about current therapeutic approaches, as well as experimental treatments that are in the pipeline.
