News $5M in Grants to Support Work into Treatments, Biomarkers for ALS and Frontotemporal Degeneration

Columns, Joyful Sorrow - a Column by Kristin Neva Just Breathe: Dealing with Chronic Stress

News First ALS Patient Enrolled in Phase 1 Trial of AP-101, AL-S Pharma AG Announces

Columns, Notes From the ALS Front - a Column by Rick Jobus Adding MDA’s Vast Resources to My ALS Arsenal and Giving Back

News First ALS Patient Enrolled in Phase 2/3 Trial of CuATSM, CMD Announces

News Mexiletine Reduces Frequency, Severity of Muscle Cramps in ALS, Trial Shows

News Phase 3 Trial of NurOwn Cell Therapy Fully Enrolls 200 Patients, BrainStorm Announces

News Harvard Researcher Wins 2019 AANEM Scientific Impact Award for Study of Fingolimod in ALS

Columns, Joyful Sorrow - a Column by Kristin Neva Coming Unstuck and Reaching Beyond Ourselves

News Potential Treatment of Mitochondria Seen to Delay Neurologic Symptoms in ALS Mouse Model

Columns, Notes From the ALS Front - a Column by Rick Jobus Envisioning a Bright Future for Our Survivors

News CENTAUR Phase 2 Trial of AMX0035, Potential ALS Treatment, Finishes Collecting Data

Columns, Living Well with ALS - a column by Dagmar Munn Celebrating My Public and Personal Milestones

News Reldesemtiv Slows Decline in Muscle Control Needed for Speech, Phase 2 Trial Analysis Finds

News Reldesemtiv May Reduce Functional Decline in Fast Progressing ALS, New Analysis Suggests

News U.S. Department of Defense Earmarks $758,121 to Develop RASRx1902 as Potential ALS Therapy

Columns, Joyful Sorrow - a Column by Kristin Neva Navigating ALS with Children in Tow

News CZI Awards I AM ALS $453K Grant to Share Tools That Will Speed Investigations Into ALS, Other Rare Diseases

Columns, Notes From the ALS Front - a Column by Rick Jobus Could Thinking Outside the Box Lead to a Cure for ALS?

News Animal Study Examines Familial ALS Mutations, Disruptions in the ANXA11 Gene

Columns, Living Well with ALS - a column by Dagmar Munn The View From (Down) Here

News ALS Hallmark, Clumps of TDP-43 Protein, Appears to Protect Nerve Cells, Study Reports

News Mitochondria Play a Critical Role in Neuroinflammation, Neuron Cell Death, Study Reveals

News NORD 2019 Rare Disease Summit Set for Oct. 21-22 in Washington, DC

News FDA Publishes Guidance to Help in Developing New ALS Therapies

Columns, Joyful Sorrow - a Column by Kristin Neva Accepting Help Is Hard, but Caregivers Need Respite

News New Study Sheds Light on How Electrical Signals Control, Maintain Muscle Movement

Columns, Notes From the ALS Front - a Column by Rick Jobus Showing Up with Carpe Diem Intent

News AstroRx, ALS Cell Therapy, Shows Potential to Slow Progression, Early Trial Data Show

Columns, Living Well with ALS - a column by Dagmar Munn Translating the Talking Boxes at the Drive-thru

News Synchron Successfully Completes First Clinical Implantation of Stentrode

News Healey Center at Mass General Launches First ALS Platform Trial with Five Candidate Treatments

News Study Suggests Mechanism for ALS Caused by Toxic Algae-produced Compound

Columns, Joyful Sorrow - a Column by Kristin Neva The Art of Choosing a Family-friendly Movie

News FightMND Awards Clene More Than $900K to Advance Investigational ALS Therapy

News Daiichi Sankyo Seeks Approval to Market Radicava in Brazil

News FTC Warns Companies Against Unsubstantiated Advertising of CBD Products for ALS

Columns, Living Well with ALS - a column by Dagmar Munn Smooth Out a Rough Day with This Mental Game

News Riluzole More Effective with Complementary Therapies Like Radicava, Study Suggests

News Compound in Rice Bran Oil Protects Nerve Cells in ALS Models, Study Finds

News Levosimendan May Bolster Lung Strength in ALS Patients, Phase 2 Trial Suggests

Columns, Joyful Sorrow - a Column by Kristin Neva The Clock Starts Ticking After an ALS Diagnosis

News Cannabis-based Sativex May Help Reduce Spasticity in ALS Patients, Study Suggests

Columns, Notes From the ALS Front - a Column by Rick Jobus Chairway to Heaven: My Power Wheelchair Takes Me Higher

News Dogs Who Received Riluzole Two Ways Fared Well in ALS Study

News Facial Nerve Atrophy Seen on High-resolution MRI Helps Diagnose ALS in Early Stages, Study Reports

News Study Supports Cdk5 as Therapeutic Target for ALS

Social Clips Check Out Our ALS News Today Multimedia Content

News Researchers Uncover HSP90 Mechanism That May Help Explain Motor Nerve Death

Columns, Joyful Sorrow - a Column by Kristin Neva Desperate Places Don’t Always Come with a Choice

News Mutations in FUS Gene Affects Growth and Workings of Motor Neuron Axons, Study Shows

Columns, Notes From the ALS Front - a Column by Rick Jobus Navigating the Chutes and Ladders of ALS: Happy Labor Day

News Neurofilament Light Chain Levels Able Blood Marker of Likely ALS Progression, Study Finds

Columns, Living Well with ALS - a column by Dagmar Munn Want to Slow Down Your ALS? Try Smiling!

News Measures of Lung Health Help to Predict Likely Outcomes in ALS Patients, Study Suggests

News ‘Disorder’ Film Festival Offers Look at Siblings Touched by Rare Diseases

News Energy Demands to Counter Gravity in Vertical Neurons May Lie at Origin of ALS, Study Proposes

Columns, Joyful Sorrow - a Column by Kristin Neva Suffering Connects Us All

News New Data on Structure, Function of SARM1 Protein May Aid Design of ALS Therapies

News Orphazyme Partnership to Run Through Extension of Phase 3 Arimoclomol Study

News At NY Genome Center, Legal Expert Presents Ethical Dilemmas in Gene Editing

Columns, Living Well with ALS - a column by Dagmar Munn ALS and My Hardly Mobile Phone

News Changes in Lipid Levels and Metabolism in Spinal Cord Mirror ALS Progression, Early Study Suggests

News New Dynamic Neck Brace May Improve Head, Neck Range of Motion for ALS Patients, Study Says

News Poorer Outcomes Likely in Those with Rapid Weight Loss Early in ALS Course, Study Suggests

Columns, Joyful Sorrow - a Column by Kristin Neva We Have No Guarantees with ALS, but We Do Have Choices

News $3.1 Million Grant to Help Find Therapies Targeting Neuron Loss in ALS

Columns, Notes From the ALS Front - a Column by Rick Jobus ALS: The Musical

News MSD and Francis Crick Institute Teaming Up for Better Understanding of ALS

Columns, Living Well with ALS - a column by Dagmar Munn To Bank or Not to Bank? I’m Voicing My Opinion

News Neuropore’s NPT520-34 Given FDA’s Orphan Drug Designation for ALS Treatment

News Motor Neurons in Familial ALS Have Mutation-Specific Alterations in Glutamate Signaling, Study Found

News Nebraska’s Neena Nizar Seeks Cure for Jansen’s, One of World’s Rarest Diseases

Columns, Joyful Sorrow - a Column by Kristin Neva Learning New Skills I Wish I Didn’t Need

News Protein Clusters Move Along Cells to Drive Immune Response, Study Suggests

News New Split-Hand Index Identifies ALS Patients at Early Disease Stages, Study Shows

Columns, Notes From the ALS Front - a Column by Rick Jobus Advancing Potential ALS Treatments Is Like Accelerating a Glacier

News AC Immune, UPenn Partner to Study How TDP-43 Protein Clumps Inside Nerve Cells

News China Becomes 6th Country to Approve Edaravone Infusion Therapy for ALS

News Complete Loss of SOD1 Function Leads to Severe Motor Problems, Study Says in Warning to Researchers

Columns, Joyful Sorrow - a Column by Kristin Neva Normal Déjà Vu: Life As We Used to Know It

News Altered Gut Microbiota in ALS Patients Could Drive Digestive Problems, Study Suggests

Columns, Notes From the ALS Front - a Column by Rick Jobus Wheels Within Wheels: Life and Consciousness Require Movement

News Underweight ALS Patients at Risk for Poorer Outcomes at Later Stages of Disease, Study Suggests

Columns, Living Well with ALS - a column by Dagmar Munn Chasing Down My ‘Someday-itis’

News Animal Study Links Inactivation of the Autophagy Gene ATG7 to the Onset of ALS, FTD

News ALS Patients Have Impaired Connectivity in Certain Brain Regions, Study Suggests

News Noninvasive Ventilation Not Likely to Help ALS Patients with Poorer Breathing Control, Study Finds

News Rare Disease Groups Seek Public Support to Renew Newborn Screening Act in Senate

Columns, Joyful Sorrow - a Column by Kristin Neva When Safety Concerns Begin to Override the Need for Independence

News Optimizing the Diet for the ALS Patient: A Nutritionist’s View

News Oklahoma Ranks Lowest on Programs Key to Rare Diseases on NORD’s 2019 State Report Card

News More Than Half of ALS Cases Have a Genetic Cause; Women Have Greatest Risk of Developing the Disease, Irish Study Suggests

News Targeting a Single Gene May Help Halt Production of Toxic Proteins in ALS, Study Suggests

News FDA Names APB-102, Potential Gene Therapy for Familial ALS, an Orphan Drug

News Cognitive Problems Have Limited Impact on Quality of Life in ALS, Study Suggests

News Frequent Weekly Exercise Sessions Don’t Bring Greater Benefit, Small Study Suggests

Columns, Joyful Sorrow - a Column by Kristin Neva Defining The Relationship: We’re More than Our Roles

News Gut Microbiome May Help Slow ALS Progression, Study Indicates

Columns, Notes From the ALS Front - a Column by Rick Jobus A Few of My Favorite Words to Live By