New analyses of data from two Phase 2 clinical trials and observational studies suggest that changes in blood levels of neurofilament light chain (NfL), a biomarker of nerve damage, may help predict which people with amyotrophic lateral sclerosis (ALS) are more likely to experience clinical benefits with Clene’s…
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Neurosense Therapeutics plans to seek Health Canada approval by the end of the year for PrimeC, its experimental oral therapy for amyotrophic lateral sclerosis (ALS). The planned new drug submission (NDS) filing follows completion of a pre-NDS process and finalization of the related meeting minutes. The process is…
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People whose jobs expose them to pesticides may be more likely to develop amyotrophic lateral sclerosis (ALS) than workers who aren’t exposed, according to a systematic review and meta-analysis. Researchers found that occupational pesticide exposure was associated with a higher risk of developing ALS. Among different pesticide classes, exposure…
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People who sustain a traumatic brain injury (TBI) are more likely to die within two years from amyotrophic lateral sclerosis (ALS), according to a new analysis. But the association may reflect an early manifestation of the disease, rather than a cause. Researchers said a phenomenon called reserve causation may…
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My husband, Todd, and I recently finished watching the NBC series “The Good Place,” a comedy that explores some of life’s big questions about meaning. In the season three finale, the character Eleanor Shellstrop searches for the answer that will make everything make sense as she tries to…
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Adding a blood test that measures nerve damage or a test of brain activity to standard diagnostic criteria may help doctors diagnose amyotrophic lateral sclerosis (ALS) more accurately, a study suggests. Researchers found that incorporating either blood levels of neurofilament light chain (NfL), a biomarker of nerve cell damage, or…
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Treatment with a novel one-time gene therapy improved motor function and extended survival in a mouse model of amyotrophic lateral sclerosis (ALS) driven by mutations in the SOD1 gene, according to researchers from the University of Massachusetts Chan Medical School. The results, the team noted,…
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Becoming educated and informed about ALS is a good first step. Here you’ll find general information about the disease, including diagnosis, symptoms, and causes.
It helps to know others have been where you are now. Here’s a collection of our columnists’ words of wisdom to help you along on your ALS journey.
There is no cure for ALS yet, but here you can find more information about current therapeutic approaches, as well as experimental treatments that are in the pipeline.
