Cases of motor neuron diseases — including amyotrophic lateral sclerosis (ALS), the most common of these — are increasing in European countries. A study suggests the reason is not solely because of an aging population, though more people are living longer and neurodegenerative diseases are more common in older…
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Masitinib treatment was linked to a nearly doubled five-year survival rate among people with amyotrophic lateral sclerosis (ALS), with higher survival rates seen among patients with slower disease progression and those who started treatment before experiencing a complete loss of functionality. That’s according to new analyses from the…
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Neurosense Therapeutics said it recently held a “constructive” meeting with Health Canada to discuss potential regulatory pathways for PrimeC, its experimental oral therapy for amyotrophic lateral sclerosis (ALS). The meeting focused on the company’s proposed new drug submission (NDS) strategy and the clinical, biomarker, and long-term outcomes data…
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Last summer, a large limb on our old mountain ash died, and this spring, our teenage son cut it off, leaving only one limb coming out of the stump of a once beautiful tree. “Is it time to take it down?” I asked my husband, Todd. “I think so,” he…
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Researchers using a fish model of amyotrophic lateral sclerosis (ALS) found that damage to the cerebellum — a brain region not traditionally associated with ALS — begins before motor symptoms emerge. This damage appears to be driven by reduced levels of PAICS, an enzyme involved in the production of…
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A team at Stanford University has received a $13 million grant to uncover previously unknown genetic causes of amyotrophic lateral sclerosis (ALS), with the goal of identifying targets for future treatments. The grant, awarded by the California Institute for Regenerative Medicine (CIRM) to a team led by Stanford…
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The statistical methods scientists use to analyze outcomes from clinical trials in amyotrophic lateral sclerosis (ALS) vary widely, and these differences may make some trials prone to generating misleading results, a study found. The researchers focused on analysis of the ALS Functional…
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Becoming educated and informed about ALS is a good first step. Here you’ll find general information about the disease, including diagnosis, symptoms, and causes.
It helps to know others have been where you are now. Here’s a collection of our columnists’ words of wisdom to help you along on your ALS journey.
There is no cure for ALS yet, but here you can find more information about current therapeutic approaches, as well as experimental treatments that are in the pipeline.
