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August 14, 2020August 14, 2020

New ALS Chip Model Closely Mimics Disease, May Aid Research

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Researchers report having created a new human-on-a-chip model, one able to more accurately simulate the clinical features of amyotrophic lateral sclerosis (ALS) in people. The chip uses motor neurons — ... Read more

August 13, 2020August 14, 2020

Nerve Cell Injury and Chronic Inflammation Need Be Focus of ALS Research, Study Argues

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The greater incidence of amyotrophic lateral sclerosis (ALS) among professional athletes and people with head trauma, and the faster functional decline seen in animal models after localized nerve injury, ... Read more

August 12, 2020August 13, 2020

Seelos to Proceed With Phase 2b/3 Trial Investigating SLS-005 for ALS

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Seelos Therapeutics has received a notification from the U.S. Food and Drug Administration (FDA) permitting the launch of its Phase 2b/3 clinical trial investigating SLS-005 (trehalose) as a treatment ... Read more

August 11, 2020August 11, 2020

New Streaming Channel Showcases Rare Disease Films

News, syndicated

When the COVID-19 pandemic forced the postponement of a rare disease film festival originally slated for May, its organizers set out to find a new way to bring the ... Read more

August 11, 2020August 12, 2020

Aural Analytics’ Speech Technology Added to HEALEY ALS Platform Trial

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Aural Analytics’ speech-based digital technology will be used to measure changes in speech in people with amyotrophic lateral sclerosis (ALS) as endpoints for the HEALEY ALS Platform Trial, which ... Read more

August 10, 2020August 10, 2020

AC Immune Working to Move TDP-43 Antibody Into Clinical Testing for ALS

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AC Immune is planning to advance its investigational anti-TDP-43 antibody into clinical testing for neurodegenerative diseases, like amyotrophic lateral sclerosis (ALS), in which TPD-43 protein aggregates play a major ... Read more

August 7, 2020August 7, 2020

Paper Explores Whether Lou Gehrig Experienced a Temporary ALS Reversal in 1938

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For three weeks during Lou Gehrig’s final season, the baseball legend appeared to shake off his symptoms of amyotrophic lateral sclerosis (ALS) and regain his flagging prowess. Richard Bedlack, ... Read more

August 6, 2020August 6, 2020

First Patients Enrolled in Pivotal HEALEY ALS Trial of Multiple Therapies

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The first platform trial for amyotrophic lateral sclerosis (ALS), designed to assess multiple treatment candidates simultaneously with a goal of accelerating the development of ALS therapies, has enrolled its ... Read more

August 5, 2020August 5, 2020

AstroRx Slows ALS Progression at All Doses Tested, Trial Shows

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Kadimastem’s cell therapy candidate, AstroRx, significantly lowers the rate of disease progression in people with amyotrophic lateral sclerosis (ALS) for at least three months after treatment, updated findings from the ... Read more

August 4, 2020August 4, 2020

ALS Researchers Probe Cerebrospinal Fluid’s Role in Motor Neurons

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The clear, colorless liquid that fills and surrounds the brain and spinal cord in people with amyotrophic lateral sclerosis (ALS) seems to induce early neurodegeneration events in healthy motor ... Read more

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