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March 26, 2019March 26, 2019

Long-term Exposure to Mercury Linked to ALS in Older Patients, Case Report Suggests

News

Long-term mercury exposure over a period of years may increase the risk of amyotrophic lateral sclerosis later (ALS) in life, a case report suggests. The study, “Heavy metal intoxication ... Read more

March 25, 2019March 25, 2019

MRI Can Detect Difficult-to-Assess Muscle Damage in ALS, Small Study Reports

News

Magnetic resonance imaging (MRI) may help detect muscle damage in amyotrophic lateral sclerosis (ALS) patients, in particular muscles that are difficult to access using standard techniques, a small study ... Read more

March 22, 2019March 22, 2019

Patient-derived Cell Model for Use in ALS Research Wins International 3Rs Prize

News

A model of motor neuron disease based on patient-derived stem cells won the 2018 International 3Rs Prize for its potential to lessen or replace the use of animals as models in ... Read more

March 21, 2019March 21, 2019

Amylyx Completes Patient Recruitment for Phase 2 Study Testing AMX0035 for ALS

News

Amylyx has completed patient recruitment for the Phase 2 clinical trial CENTAUR, which addresses the safety and effectiveness of AMX0035 as an oral treatment for amyotrophic lateral sclerosis (ALS). In 2017, Amylyx ... Read more

March 20, 2019March 20, 2019

Bacteria and Fungi Found in Central Nervous System of ALS Patients, Study Reports

News

Several species of bacteria and fungi were found living in the central nervous system (CNS) of patients with amyotrophic lateral sclerosis (ALS) that could potentially be related to the ... Read more

March 19, 2019March 19, 2019

Nerve-protecting Cells Hold Potential in Development of ALS Therapies

News, Therapies

A specific type of supporting cells called Schwann cells protect against nerve degeneration induced by the blood-clotting protein thrombin, according to new research in mice. Researchers say the findings ... Read more

March 18, 2019March 18, 2019

Young Researcher Awarded for Work on Processes Driving Development of ALS and Frontotemporal Dementia

News

Biochemist Dorothee Dormann, PhD, at the Ludwig Maximilians University, in Munich, was awarded the 2019 Paul Ehrlich and Ludwig Darmstaedter Prize for Young Researchers for her groundbreaking work showing ... Read more

March 15, 2019

Caregiver Burden Tied to Patients’ Level of Apathy in Study

News

Higher levels of apathy — particularly its behavioral symptoms — in people with amyotrophic lateral sclerosis (ALS) are associated with a degree of greater burden for caregivers, according to ... Read more

March 14, 2019March 14, 2019

Brexit Could Have Real Effects for UK Rare Disease Patients, Experts Warn

News

Madeline Collin, a 24-year-old activist with Gaucher disease, worries that patients like her will suffer deeply if Britain leaves the European Union (EU), as scheduled, at the end of ... Read more

March 14, 2019March 14, 2019

ALS MRI Marker May Facilitate Diagnosis and Monitoring, Study Finds

News

A magnetic resonance imaging (MRI) marker may facilitate amyotrophic lateral sclerosis (ALS) patients’ diagnosis and disease monitoring, a study finds. The study, “Is the Hypointensity in Motor Cortex the Hallmark of Amyotrophic ... Read more

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