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August 23, 2019August 23, 2019

Poorer Outcomes Likely in Those with Rapid Weight Loss Early in ALS Course, Study Suggests

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People with rapid weight loss in the earlier stages of amyotophic lateral sclerosis (ALS) — before invasive ventilation is needed to support breathing — are more likely to have a ... Read more

August 22, 2019August 22, 2019

$3.1 Million Grant to Help Find Therapies Targeting Neuron Loss in ALS

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A $3.1 million grant from the National Institute on Aging (NIA) is intended to help two scientists at Northwestern University find new treatments for amyotrophic lateral sclerosis (ALS). The ... Read more

August 21, 2019August 21, 2019

MSD and Francis Crick Institute Teaming Up for Better Understanding of ALS

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Pharmaceutical company MSD and the Francis Crick Institute are partnering to try to learn more about what causes motor neurone disease (MND), also known as amyotrophic lateral sclerosis (ALS), ... Read more

August 20, 2019August 20, 2019

Neuropore’s NPT520-34 Given FDA’s Orphan Drug Designation for ALS Treatment

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The U.S. Food and Drug Administration (FDA) has granted orphan drug status to NPT520-34, an investigational anti-neuroinflammatory molecule, for the treatment of amyotrophic lateral sclerosis (ALS), Neuropore Therapies announced. “We are ... Read more

August 19, 2019August 19, 2019

Motor Neurons in Familial ALS Have Mutation-Specific Alterations in Glutamate Signaling, Study Found

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Stem cell-derived motor neurons from people with familial amyotrophic lateral sclerosis (ALS) have mutation-specific alterations in glutamate receptors and calcium signals, which may alter nerve signaling and play a role ... Read more

August 16, 2019August 16, 2019

Nebraska’s Neena Nizar Seeks Cure for Jansen’s, One of World’s Rarest Diseases

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Imagine living your whole life with a painful disease so rare that only 25 others worldwide have what you have. And that you’re one of just six such people ... Read more

August 15, 2019August 16, 2019

Protein Clusters Move Along Cells to Drive Immune Response, Study Suggests

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Clusters containing a protein called LAT use specific adapters to move and drive the activation of T-cells to fight off infection, according to a study, the findings of which ... Read more

August 14, 2019

New Split-Hand Index Identifies ALS Patients at Early Disease Stages, Study Shows

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Scientists have created a new type of split-hand index — which identifies the loss of the pincer grasp — that is able to distinguish people with amyotrophic lateral sclerosis ... Read more

August 13, 2019August 13, 2019

AC Immune, UPenn Partner to Study How TDP-43 Protein Clumps Inside Nerve Cells

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Biopharma AC Immune has entered a research collaboration with scientists at the Perelman School of Medicine at the University of Pennsylvania (UPenn) to uncover why TDP-43 misshapes and accumulates ... Read more

August 12, 2019August 12, 2019

China Becomes 6th Country to Approve Edaravone Infusion Therapy for ALS

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People in China with amyotrophic lateral sclerosis (ALS) can now access edaravone (brand names Radicava, Radicut, among others), following its approval by the National Medical Products Administration, the country’s ... Read more

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