AP-101, AL-S Pharma’s amyotrophic lateral sclerosis (ALS) therapy, was safe and well tolerated and led to clinically meaningful benefits for breathing and survival after one year of treatment. That’s according to topline data from a now-complete Phase 2a study (NCT05039099) that tested the therapy in 73 adults with…
“I should be an ALS comedian. I know I could, too — that is, if it weren’t for my darn ALS.” That’s what I tell myself on the days when life’s funny moments come at me fast and furious. It’s another example of how this disease keeps on challenging…
Analyzing single strands of hair has shown researchers that the dynamics of certain metal molecules, such as copper and zinc, in the body are altered in amyotrophic lateral sclerosis (ALS). The scientists hope to build on this discovery to develop a new, noninvasive diagnostic test for the neurodegenerative condition.
Five students from across Canada whose lives have been directly affected by amyotrophic lateral sclerosis (ALS) received scholarships to help them pursue post-secondary education. Each ALS Canada Kevin Daly Bursary recipient will receive $2,500 for the 2025–2026 academic year. The scholarship program is designed for students with a parent,…
A clinical trial in Australia and Europe will test whether trimetazidine, a medication commonly used to treat heart conditions, could help improve function and quality of life for amyotrophic lateral sclerosis (ALS) patients. The trial, led by University of Queensland researcher Shyuan Ngo, PhD, and her team at the…
Before my husband, Todd, had ALS, he enjoyed cooking. He often made omelets on Saturday mornings. He was skilled with a chef’s knife and cut ingredients quickly and finely before cooking the egg to perfection. I miss eating his omelets. Although I do all the actual cooking now,…
Through analyses of blood samples from hundreds of patients, researchers have developed a highly accurate test for diagnosing amyotrophic lateral sclerosis (ALS). The test is based on a unique protein signature in the blood that may be able to detect ALS-related changes up to 10 years before symptoms of…
Until recently, my language skills and speech were best buddies. They were happily and symbiotically entwined, each supporting the other with comfort and ease. Language — the software system — was the one with all the good ideas, reacting to the environment in milliseconds like a gleeful toddler and formulating…
Coya Therapeutics is preparing to launch a Phase 2 clinical trial in the U.S. to test its COYA 302 as an amyotrophic lateral sclerosis (ALS) treatment. The company said the U.S. Food and Drug Administration accepted its investigational new drug (IND) application after it submitted additional data the agency…
Often I do some of my deepest thinking when I’m alone in the car. I regularly drive 35 minutes to ride my horse, and I like to spend that time in silence. That’s when I think about people to contact or items on my to-do list for the week ahead.
