Urine levels of a protein component known as p75ECD may be a valuable biomarker for diagnosing and monitoring the progression of amyotrophic lateral sclerosis (ALS), according to a study. The research, “Urinary p75ECD: A Prognostic, Disease Progression, And Pharmacodynamics Biomarker In ALS,” was published in the journal Neurology. The National…
Urine Levels of Protein p75ECD May Help Diagnose, Monitor ALS, Study Reports
Schizophrenia in relatives of amyotrophic lateral sclerosis (ALS) patients is caused by shared genetic factors that increase the risk of both conditions, researchers confirmed. This prompted them to contend that scientists should view ALS as a disease of brain connections, rather than of individual brain cells. The way to treat…
It’s devastating when a friend or family member is diagnosed with a terminal illness. You want to reach out to help, but you’re often unsure how to handle the situation and what to say—fearful of saying the wrong thing. We’ve compiled a list of ways to help support your loved through…
Poor bone health that makes people vulnerable to fractures may be a risk factor for the development of amyotrophic lateral sclerosis (ALS), according to a study. The research, “Association Of Fractures With The Incidence Of Amyotrophic Lateral Sclerosis,” was published in the journal Amyotrophic Lateral Sclerosis and Frontotemporal…
An opinion piece titled “A serious and often overlooked issue for patients with brain diseases: Swallowing” by Dr. Donald Bolser, a professor at the University of Florida recently published in the independent news and views website The Conversation, highlights the importance of detecting and treating impaired swallowing in people with brain disease.
Most of us have probably been reminded to take our vitamins, or pushed to eat something because it’s “full of vitamins”—and it’s true, getting vitamins is incredibly important. Especially during the winter when some people experience Seasonal Affective Disorder, which can be impacted by low levels of vitamin D. But that’s not…
Life is tough for people with a chronic illness, but through the pain and the fatigue and all the other symptoms and side effects, they show an extraordinary passion for life and try to achieve as much as possible. With help from themighty.com, we’ve compiled a list of eight remarkable things…
Mutations in a protein called VCP lead to problems with energy production in muscles and the onset of IBMPFD, a neurodegenerative disease similar to amyotrophic lateral sclerosis (ALS), a study reports. VCP inhibitors were seen to reverse the processes that damaged and killed muscle cells, and may be of value in ALS. The study, “…
Masitinib met its main Phase 2 and 3 clinical trial goal of improving the functioning of amyotrophic lateral sclerosis (ALS) patients, according to its maker, AB Science SA. The randomized, double-blind AB10015 (NCT02588677) trial compared the effectiveness and safety of a combination of masitinib and riluzole with a combination of…
Researchers have identified molecular mechanisms that lead to the abnormal and toxic accumulation of proteins within neurons, according to a new study. For amyotrophic lateral sclerosis (ALS) patients, these findings may pave the way for the design of new therapies by targeting protein aggregation in the brain. The study, titled “Phase…
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