In ALS Study, Essential Protein Seen as Promising New Theurapeutic Target

In ALS Study, Essential Protein Seen as Promising New Theurapeutic Target

Researchers have identified an essential protein, Pur-alpha, for motor neuron cells’ mechanisms of defense against external stress and degeneration and also as a potential new therapeutic target for the treatment of amyotrophic lateral sclerosis (ALS, or Lou Gehrig’s disease). The research paper, “Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates…

Key Players in Neuroinflammation Tied to ALS, Depression Highlighted

A recent review summarized the effects of immune system dysregulation and neuroinflammation in the regulation of critical pathways associated with depression and other brain disorders, including amyotrophic lateral sclerosis (ALS). The researchers specifically focused on extracellular vesicles (EVs) as potential biomarkers and drug delivery vehicles. The review, “Neuroinflammation and Depression: Microglia Activation, Extracellular Microvesicles…

ALS in the Military

In this ALS Association video, learn more about our military heroes who were being diagnosed and dying from Lou Gehrig’s disease in the years following the operation Desert Storm in 1981. Learn more about ALS here: https://bit.ly/ALSNewsToday…

Last Week’s Top-3 Most Read Posts On ALS

Read the Articles Here: ALS Stem Cell Therapy Seen to Benefit Patients in First Round of Clinical Tests ALS Patients Show Increased Response to Specific Receptor in Spinal Cord ALS Severity, Duration May Be Linked to Glutamate Toxicity  …

ALS – What are the Symptoms?

Meet Dr. Bradley Jacobs of premier health specialists, the Clinical Neuroscience Institute. In this video, he explains some of the symptoms of ALS and what is does to your body through out time. Learn more about ALS: https://bit.ly/ALSNewsToday…

ALS: Q&A with Anthony Carbajal

Meet Anthony Carbajal. You might know him for being one of the guys who started sharing word about ALS  and also the Ice Bucket Challenge. His first video was really emotional and touching, so much that it even got him to go to The Ellen Show, among other several…

ALS Severity, Duration May Be Linked to Glutamate Toxicity

The ratio of N-acetyl aspartate (NAA) to glutamate is related to disease duration in patients with amyotrophic lateral sclerosis (ALS), a finding that supports the notion of glutamate toxicity as a contributing factor in ALS pathology. Earlier studies have indicated that the neurotransmitter glutamate is involved in ALS. People with sporadic ALS…