The Wadsworth Brain-Computer Interface (BCI) can help amyotrophic lateral sclerosis (ALS) patients who are severely disabled to communicate while in the home, a study reports, especially those in fairly stable health. Improvements underway to this system, which relies on brain signals rather than muscles necessary for speaking or writing, are…
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Cytokinetics has awarded the ALS Association Golden West Chapter with its first communications fellowship, part of a company initiative directed at nonprofit organizations to increase public education and awareness of their programs and care services, as well as to elevate patients’ voices. “As a longstanding partner…
The balance between copper isotopes (variants) – but not copper levels – is disrupted in patients with amyotrophic lateral sclerosis (ALS), according to a recent study. Copper isotope composition potentially may be used as a biomarker of ALS, distinguishing it from other neurodegenerative diseases, such as Alzheimer’s. The study, “…
Combining structural brain imaging with molecular and clinical biomarkers allows for a detailed assessment of a patient’s clinical state, regardless of age and amyotrophic lateral sclerosis progression, a new study suggests. The study, “Combinatory Biomarker Use of Cortical Thickness, MUNIX, and ALSFRS-R at Baseline and in Longitudinal Courses of…
Impaired tightening of the pharynx is associated with inefficient swallowing in patients with amyotrophic lateral sclerosis (ALS), according to a new study. The study, “Reduced pharyngeal constriction is associated with impaired swallowing efficiency in Amyotrophic Lateral Sclerosis (ALS),” appeared in the journal Neurogastroenterology & Motility.
Treatment with extracts from the Withania somnifera plant improved motor performance and delayed disease progression in mice with amyotrophic lateral sclerosis (ALS), according to researchers. The study, “Protective effects of Withania somnifera extract in SOD1G93A mouse model of amyotrophic lateral sclerosis,” was published in the journal Experimental Neurology. ALS generally develops sporadically, indicating that in…
A decline of 25 percent each year in cough peak flow, a test of cough strength and airway clearance, is a predictor of poor survival in people with amyotrophic lateral sclerosis (ALS), a small study from Japan reports. The study “Cough peak flow decline rate predicts…
Federal healthcare databases, especially Medicare, are a valuable resource in identifying cases of amyotrophic lateral sclerosis (ALS) in the U.S. population, and may help in tracking the prevalence of other neurological diseases as well, a group of researchers report. The study, “Estimation of the Prevalence of Amyotrophic Lateral Sclerosis in…
MicroRNA Known to Be Abundant in ALS Patients May Offer Way of Treating Disease, Study Suggests
The microRNA-218 (miR-218), produced at excessive levels by damaged or dying nerve cells, may be a therapeutic target for amyotrophic lateral sclerosis (ALS), an animal study suggests. This molecule was found to disrupt the normal function of astrocytes, star-shaped glial cells found throughout the central nervous system (brain…
A newly developed test, known as the arrows and colors cognitive test, can be used to measure cognition in amyotrophic lateral sclerosis (ALS) patients who have severe motor and verbal disabilities. A study about that assessment tool, “The Arrows and Colors Cognitive Test (ACCT): A new verbal-motor free cognitive…