RNA molecules that are not supposed to leave the cell nucleus might be responsible for driving neuronal cell death in people with amyotrophic lateral sclerosis (ALS), researchers from England’s University of Sheffield report in a study that suggests a way to prevent that from happening. The research team discovered just how…
This video from Alisa Apreleva is all about an awareness campaign in Moscow, Russia, that’s helping to highlight amyotrophic lateral sclerosis (ALS). MORE: What research is being done on ALS? The video features Russian recording artists and patients in various stages of the disease singing a specially written and composed…
Although known risks factors for ALS include age, male sex, and cigarette smoking, how occupations can influence ALS or other neurodegenerative diseases is less understood. A new study, however, finds that those who have high-status careers, often called white collar workers, face higher Amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD)…
Inflammation in the spinal cord, at least in part mediated by a molecule called PGE2, likely contributes to the disease processes of amyotrophic lateral sclerosis (ALS), researchers from Nihon University in Japan suggest. Their study, published in the journal Neurochemistry International, suggests that the molecule signals through one…
Around 90 percent of amyotrophic lateral sclerosis (ALS) cases are considered sporadic with no family history of the disease, but the remaining 10 percent are cases where ALS runs in the family. Often patients with familial ALS (FALS) also suffer from frontotemporal dementia, which is due to mutated genes that get passed down through the family.
In this video from ITV’s This Morning, television presenter Charlotte Hawkins talks about her father’s journey with motor neuron disease (MND), which is also known as amyotrophic lateral sclerosis (ALS). She highlights how lonely people can feel living with the disease, particularly when they lose the…
Mutations in the TDP-43 gene might not be causing the disease changes seen in amyotrophic lateral sclerosis (ALS) on their own, but might need additional environmental or genetic factors to trigger disease. This was the conclusion of scientists at the Oregon Health & Science University who studied mutant forms…
Ipsen Biopharmaceuticals has entered an exclusive three-year agreement with Saol Therapeutics to promote Dysport (abobotulinumtoxinA), a therapy indicated for injection in adults with spasticity and in children with lower limb spasticity – common in amyotrophic lateral sclerosis (ALS) patients. Under the agreement, Saol will set up a…
Worldwide Clinical Trials was selected as the Clinical Research Organization (CRO) to run a Phase 3 study of the investigational stem-cell therapy NurOwn for the treatment of amyotrophic lateral sclerosis (ALS). BrainStorm Cell Therapeutics, which developed NurOwn, expects the collaboration will provide all of the necessary requirements to pursue the placebo-controlled,…
Mitsubishi Tanabe Pharma America (MT Pharma America) has enrolled more than 700 sites of care in its newly created National Infusion Center Directory to help physicians identify local infusion centers for amyotrophic lateral sclerosis (ALS) patients who are prescribed Radicava (edaravone).
