Amyotrophic lateral sclerosis (ALS) is a serious disorder that causes progressive loss of motor neurons, the nerve cells that control muscle movement. Most patients will experience some disability, including difficulty swallowing and slurred speech, as a result of the loss of these nerve cells. What is speech therapy? Speech therapy…
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder associated with the death of motor neurons. These are nerve cells that control the voluntary muscles, which are essential for movement. As the condition progresses, the muscles weaken and waste away, resulting in a loss of muscle control. Although ALS…
The brain’s waste clearance pathway, known as the glymphatic system, could enable more efficient delivery of therapeutics into the brain for the treatment of disorders such as amyotrophic lateral sclerosis (ALS), Alzheimer’s, Parkinson’s, and brain cancer, according to a study. The study, “Transcranial optical…
Health conditions that may lead to a faster metabolism, or higher metabolic rate, may contribute to the development of amyotrophic lateral sclerosis (ALS), a large-scale, population-based study suggests. The study, “Finding diseases associated with amyotrophic lateral sclerosis: a total population-based case–control study,” was published in the…
Last updated Jan. 16, 2023, by Teresa Carvalho, MS Fact-checked by Inês Martins, PhD What is Tiglutik for ALS? Tiglutik (riluzole oral suspension) is a liquid formulation of riluzole approved for treating amyotrophic lateral sclerosis (ALS). It can be taken orally or administered through a feeding tube…
Mutations that affect a particular molecular pathway essential to protein production further support reports of a link between amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA). The study detailing this finding, “The neurodegenerative diseases ALS and SMA are linked at the molecular level via the ASC-1 complex,”…
A gene therapy effectively and safely lowered the production of a key amyotrophic lateral sclerosis (ALS) protein called superoxide dismutase 1 (SOD1) in primates, according to a new study. “This level of silencing, coupled with the lack of adverse effects, suggests that this approach to treating ALS should be…
While genetics alone do not cause amyotrophic lateral sclerosis (ALS), a large number of genetic mutations have been associated with the neurodegenerative disease. Such mutations can increase a person’s risk of developing ALS, also known as Lou Gehrig’s disease, which affects motor neurons, the nerve cells that…
Amyotrophic lateral sclerosis (ALS) is a severe neurodegenerative disease characterized by the progressive loss of motor neurons, nerve cells that control the voluntary muscles. This leads to symptoms that include overall muscle weakness, causing difficulties with moving, breathing, eating, and speaking. There is no…
Amyotrophic lateral sclerosis (ALS) is a progressive neurological disorder that leads to the loss of nerve cells. The disease is caused by genetic mutations, but also may be caused by environmental factors such as smoking or alcohol use. Diagnosing ALS can be difficult and multiple tests usually…
