‘Jumping Genes’ Identified as Possible Cause of ALS, Linked to TDP-43 Protein Accumulation

A new study identified a group of sporadic amyotrophic lateral sclerosis (ALS) patients whose disease may arise from a group of “jumping genes” unleashed when TDP-43 protein accumulates in clumps in the brain and spinal cord. These “jumping genes” — which can randomly hop from one location on…