AC Immune, UPenn Partner to Study How TDP-43 Protein Clumps Inside Nerve Cells
Biopharma AC Immune has entered a research collaboration with scientists at the Perelman School of…
Articles by Ana Pena, PhD
China Becomes 6th Country to Approve Edaravone Infusion Therapy for ALS
People in China with amyotrophic lateral sclerosis (ALS) can now access edaravone (brand names Radicava, Radicut, among…
Noninvasive Ventilation Not Likely to Help ALS Patients with Poorer Breathing Control, Study Finds
Noninvasive ventilation (NIV) can be ineffective in preventing episodes of upper airway obstruction in amyotrophic lateral sclerosis (ALS)…
Specific Nerve and Other Cells in Spine Unique to ALS Patients and May Be Early Markers of Disease, Study Says
Specific populations of neurons and associated cells in the spinal cord of people with sporadic amyotrophic lateral sclerosis (ALS)…
Study in Twins Links Age-Related Changes in DNA Methylation with ALS
A study in identical twins or triplets found that changes in DNA marks, collectively known as DNA methylation and typically associated…
Add-on Masitinib Slows Progression of ALS, Final Phase 2/3 Trial Results Show
Masitinib in combination with Rilutek (riluzole) slows functional decline of patients with amyotrophic…
By Capturing Patients’ Feelings of Dyspnea, DALS-15 Scale May Ably Spot Those Needing Help with Breathing
A new patient-reported way of measuring shortness of breath in amyotrophic lateral sclerosis (ALS), called the Dyspnea-ALS-Scale or DALS-15, can…
High Body Mass Index and Weight Gain with Aging Linked to Lower Risk of ALS in Norwegian Population Study
People who have a high body mass index or gain weight as they age may be at a lower risk…
SOD1 Enzyme Clumps May Expose Cells to DNA Damage in Some ALS Patients, Study Suggests
The enzyme superoxide dismutase 1 (SOD1) forms clumps inside the cells of some people with sporadic amyotrophic lateral…
ALS Type 8 May Cause Cognitive and Behavioral Changes, Leading to Depression, Study Suggests
People with familial amyotrophic lateral sclerosis (ALS) related to the gene VAPB — known as ALS type 8…