FUS Mutations Cause Most Cases of ALS in Adolescents, Literature Review Finds
When amyotrophic lateral sclerosis (ALS) symptoms emerge during adolescence, mutations in the FUS gene are likely to blame,…
Articles by Inês Martins, PhD
Plasma Creatinine Potential Biomarker of Functional Decline, Survival in ALS Patients, Study Indicates
Levels of plasma creatinine — a metabolic product of healthy muscle — are significantly associated with the functional status of…
Fasudil Shows Promising Results in 3 ALS Patients Treated Under Compassionate Use
Fasudil, approved in Japan for treating stroke patients, also is well-tolerated and prevents disease worsening in people with amyotrophic…
TBK1 Protein Has Dual Role in ALS, First Accelerating It and Later Slowing It
Mutations in the TBK1 gene — often associated with amyotrophic lateral sclerosis (ALS) — seem to have a…
Age and Sex Strongly Influence ALS Type and Symptoms, Study Finds
The onset and early progression of motor and cognitive symptoms, specific by disease type to each amyotrophic lateral sclerosis…
Phase 3 Trial of Masitinib as Add-on ALS Treatment Cleared by FDA
AB Science plans to launch a Phase 3 clinical trial testing the safety and effectiveness of its tyrosine kinase inhibitor…
Brain Mapping Study May Be Used to Help ALS Patients Regain Motor Control
A single brain area previously thought to control only the movement of the hands and arms also may control movement…
Using Anti-diabetics, Cholesterol-lowering Medicines May Affect Risk of ALS
People with amyotrophic lateral sclerosis (ALS) are less likely to have used anti-diabetic medications in the five years…
Radicava Effective in Slowing Progression Across Year of Use, Trial Data Show
Radicava (edaravone), an approved treatment for amyotrophic lateral sclerosis (ALS), can be taken for up to one…
AstroRx Increases Ability to Perform Daily Functions in ALS Patients, Trial Results Show
Amyotrophic lateral sclerosis (ALS) patients receiving the lowest dose of Kadimastem’s cell therapy candidate, …