Posts by: Iqra Mumal

Expression of the calcium channel Cacophony in certain motor neurons restored motor defects in a fruit fly model with TDP-43 loss, a condition found in neurodegenerative diseases like amyotrophic lateral ... Read more

September 1, 2017September 1, 2017

Scientists Use Phosphorylation to Separate FUS Protein Clumps, Common in ALS, in Lab Study

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Clumps of the protein FUS, which are a pathological characteristic of ALS and frontotemporal dementia, can be prevented through a biological process called phosphorylation, a new study shows. The ... Read more

June 28, 2017June 28, 2017

New Technique Gives Researchers a Near-atom-level View of Enzyme’s Role in Correcting Misfolded Proteins

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University of Michigan and University of Pennsylvania researchers used a cutting-edge technique called cryo-electron microscopy to see how the Hsp104 yeast enzyme breaks up clumps of the misfolded proteins that are hallmarks of neurodegenerative ... Read more

June 15, 2017June 15, 2017

ALS Patients Experience Inefficient Skeletal Muscle Oxidative Function During Exercise, Study Finds

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A new study shows that patients with amyotrophic lateral sclerosis (ALS) experience decreased oxidative metabolism during exercise, and that differences among individuals in exercise capacity matches ALS clinical heterogeneity. ... Read more

June 12, 2017June 12, 2017

Dying May Be a More Positive Experience Than We Imagine, Finds Analysis of ALS Patients, Death Row Inmates

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People dying of terminal diseases like amyotrophic lateral sclerosis (ALS) and inmates on death row have something in common: their outlooks are more positive than might be expected. A recent study examining ... Read more