Posts by: Joana Carvalho

Joana Carvalho

January 10, 2019January 10, 2019

CuATSM Therapy May Slow ALS Progression, Improving Cognition and Respiration in Patients, Phase 1 Trial Shows

News

CuATSM, one of the lead investigational therapies of Collaborative Medicinal Development (CMD), may slow disease progression and improve the respiratory and cognitive function of patients with amyotrophic lateral sclerosis ... Read more

December 10, 2018December 10, 2018

Graphene May be Used to Detect Biomarkers for ALS, Study Reports

News

Graphene, a material made up of a thin sheet of carbon, may be used in the future to detect and measure biomarkers able to identify patients with amyotrophic lateral ... Read more

October 2, 2018

Bulbar-onset ALS in Patients 80 and Older May Lead to Shorter Survival, Study Reports

News

Bulbar-onset amyotrophic lateral sclerosis (ALS) is the most common form of the disease among patients 80 and older at disease onset, a factor that seems to contribute to shorter ... Read more

September 10, 2018September 10, 2018

Bulbar-onset ALS Diagnosed in Man with PNFA, Type of Frontotemporal Dementia

News

A man with progressive non-fluent aphasia (PNFA), one of the three types of frontotemporal dementia (FTD), was unusual in developing amyotrophic lateral sclerosis (ALS) with bulbar-onset one year later, a case ... Read more

August 28, 2018August 28, 2018

Combination of Imaging, Biomarkers Offers Better Assessment of ALS Patients, Study Finds

News

Combining structural brain imaging with molecular and clinical biomarkers allows for a detailed assessment of a patient’s clinical state, regardless of age and amyotrophic lateral sclerosis progression, a new study ... Read more

August 7, 2018August 7, 2018

Optimized Bi-PAP Protocol Improves ALS Patients’ Survival, Study Suggests

News

A new optimized protocol for the use of a noninvasive ventilation technique called bi-level positive airway pressure (Bi-PAP) allows patients with amyotrophic lateral sclerosis (ALS) to live twice as ... Read more

August 3, 2018

Repair Cells Change in Neurodegenerative Disorders, Promoting Muscle Wasting and Scarring, Study Says

News

Cells that normally help to repair injured muscle tissue — called fibro-adipogenic progenitors — become key players in the muscle wasting and scarring processes in neurodegenerative diseases, such as amyotrophic lateral ... Read more

July 31, 2018July 31, 2018

Axon Loss in ALS Doesn’t Appear Linked to Death-promoting Molecule, Study in Mice Reports

News

Events leading to the loss of nerve cell fibers called axons appear to take place independent of Sarm1, a molecule known to promote the death of axons in damaged nerve ... Read more

July 24, 2018July 24, 2018

TDP-43 Accumulation Causes RNA Instability in Nerve Cells of ALS Patients

News

The accumulation of TDP-43, a widely expressed nuclear protein that binds both DNA and RNA, causes RNA instability in nerve cells derived from patients with amyotrophic lateral sclerosis (ALS). ... Read more

July 16, 2018July 16, 2018

Boosting Protein with Role in Getting Nutrients to Cells Prevented Muscle Wasting in ALS Mice, Study Finds

News

Restoring or artificially raising levels of a protein found in the spinal cord, mitofusin 2, worked to prevent nerve degeneration, muscle atrophy, and paralysis in a mouse model of ... Read more

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