Posts by: Joana Carvalho

News

Scientists who dissected the structure, and mechanism of action, of the protein Cdc48 — dubbed the “Swiss Army knife of cells” — say it can be explored as a ... Read more

July 9, 2019July 9, 2019

ALS Posture Impairments May Be Marker for Disease Severity, Study Suggests

News

Posture impairments in amyotrophic lateral sclerosis (ALS) are linked to deficits in trunk control and in the mechanisms that control the body’s response to surface tilts. Moreover, these abnormalities ... Read more

June 18, 2019June 18, 2019

ACT Support Program Empowers Caregivers to Cope With Distress, Study Says

News

Caregivers of people with amyotrophic lateral sclerosis (ALS) and progressive muscular atrophy (PMA) say a Dutch support program — one based on Acceptance and Commitment Therapy — empowered them ... Read more

May 30, 2019May 30, 2019

Histamine-Related Genes May Become Biomarkers and Therapeutic Targets for ALS, Mouse Study Suggests

News

Histamine-related genes are promising disease biomarkers and therapeutic targets to slow amyotrophic lateral sclerosis (ALS) progression, a mouse study suggests. The study, “Histaminergic transmission slows progression of amyotrophic lateral ... Read more

May 16, 2019May 16, 2019

Oxford BioDynamics to Use New Technology as Partner in REFINE-ALS Biomarker Study

News

Oxford BioDynamics has joined the REFINE-ALS study, a project designed to detect and measure the levels of specific biomarkers among people with amyotrophic lateral sclerosis (ALS), Mitsubishi Tanabe Pharma ... Read more

May 13, 2019May 13, 2019

Investigational ALS Treatment NPT520-34 Begins Phase 1 Trial in Healthy Volunteers

News

NPT520-34, an investigational small molecule for the treatment of Parkinson’s disease and amyotrophic lateral sclerosis (ALS), is being tested on healthy individuals in a new Phase 1 clinical trial, its developer ... Read more

May 9, 2019May 9, 2019

#AANAM – Reldesemtiv Reduces Lung Function Decline and ALS Progression, Phase 2 Trial Shows

News

Reldesemtiv (formerly known as CK-2127107) reduces lung function decline and overall disease progression, without significant adverse events, in people with amyotrophic lateral sclerosis (ALS), a Phase 2 trial shows. ... Read more

April 26, 2019June 21, 2019

New Prognosis Model Predicts Risk of Respiratory Insufficiency or Death in ALS Patients, Study Says

News

Scientists created a new prognosis model to predict the risk of respiratory insufficiency or death within six months of follow-up in patients with amyotrophic lateral sclerosis (ALS). The study, ... Read more

April 16, 2019June 3, 2019

Enhanced Autophagy Can Alleviate Issues in ALS-linked Proteins, Study Says

News

Damaged activity of RNA-binding proteins (RBPs) associated with amyotrophic lateral sclerosis (ALS) can be alleviated by inducing autophagy, a process where cells degrade or recycle components that are damaged or no longer ... Read more

April 10, 2019May 15, 2019

Specific Molecular Patterns Could be a Strong Marker for ALS Progression and Prognosis, Study Contends

News

The patterns of methylation in arginine residues circulating in the cerebrospinal fluid — the liquid that circulates in the brain and spinal cord — could be a strong indicator of ... Read more

Posts by: Joana Carvalho

Joana Carvalho

Structure of Cdc48 May Provide Clues for Designing New ALS Therapies, Study Shows

ALS Posture Impairments May Be Marker for Disease Severity, Study Suggests

ACT Support Program Empowers Caregivers to Cope With Distress, Study Says

Histamine-Related Genes May Become Biomarkers and Therapeutic Targets for ALS, Mouse Study Suggests

Oxford BioDynamics to Use New Technology as Partner in REFINE-ALS Biomarker Study

Investigational ALS Treatment NPT520-34 Begins Phase 1 Trial in Healthy Volunteers

#AANAM – Reldesemtiv Reduces Lung Function Decline and ALS Progression, Phase 2 Trial Shows

New Prognosis Model Predicts Risk of Respiratory Insufficiency or Death in ALS Patients, Study Says

Enhanced Autophagy Can Alleviate Issues in ALS-linked Proteins, Study Says

Specific Molecular Patterns Could be a Strong Marker for ALS Progression and Prognosis, Study Contends

Pin It on Pinterest