2 Proteins Seen as Possible ALS Blood Biomarkers
Clusterin, a protein that plays a key role in motor neuron health, and ficolin-3, a protein essential…
Articles by Joana Carvalho, PhD
200 ALS Patients Finish Dosing in Phase 3 Trial of NurOwn Cell Therapy
Patient dosing has finished in the pivotal Phase 3 trial assessing the safety and efficacy of repeat administrations of…
Severe Weight Loss Linked to Higher Risk of Death in Study of Patients
Weight loss at the time of diagnosis appears common among people with amyotrophic lateral sclerosis (ALS), regardless of whether they…
Compound Found in Blackberries Prolongs Lifespan, Reduces Disease Severity in ALS Mice
Protocatechuic acid, a metabolite of one of the main substances that give blackberries and black rice their distinctive dark…
Caffeine and NAD+ Bolster Health of Motor Neurons From ALS Mouse Model
Caffeine, an antioxidant with neuroprotective properties, was seen to promote the normal development of lab-cultured motor neurons isolated…
Woman’s ALS-like Symptoms Linked to Retrovirus in Case Report
Treatment of people whose symptoms are suggestive of amyotrophic lateral sclerosis (ALS) but likely linked to a retrovirus called …
Statins Not Linked to Earlier Death Among ALS Patients in Registry Study
Statins, often prescribed to lower cholesterol levels, are not associated with poorer overall survival in people with…
Researchers Like Results of Using Nanoparticles to Carry Adapalene in ALS Mice
Injecting tiny particles carrying adapalene — an activator of the retinoic acid signaling pathway — to the brain…
Shift in Immune Cells’ Balance Linked to ALS Severity and Progression, Study Finds
A shift in the make-up of immune cells found in the blood of patients with amyotrophic lateral sclerosis (ALS)…
Discovery of Link Between Cellular Hallmarks of ALS May Lead to New Therapies
By blocking the activity of the proteasome — a complex of enzymes responsible for the destruction of unnecessary or…