Author Archives: Margarida Azevedo, MSc

Methods for Estimating ALS Heritability Reviewed in New Report

A group of researchers from the King’s College London recently published a new editorial entitled, “Heritability of Amyotrophic Lateral Sclerosis” in the journal JAMA Neurology – the official journal of the American Medical Association, that comments on the heritability estimation results of amyotrophic lateral sclerosis from a previous…

SciFluor Granted U.S. Patent for KCNQ2/3 Activator to Treat ALS and Epilepsy

The U.S. Patent and Trademark Office (USPTO) recently granted clinical stage biopharmaceutical company and subsidiary of Allied Minds, SciFluor Life Sciences, LLC, a patent for one of their novel pipeline compounds, SF0034, a potent and selective neuronal potassium channel activator that is being studied for the treatment of epilepsy, amyotrophic lateral sclerosis…

ALS Muscle Biopsies Exhibit Chronic Neurogenic Atrophy, Study Shows

Recent evidence shows that in amyotrophic lateral sclerosis (ALS), there occurs a notable deposition of abnormal ubiquitinated inclusions immunoreactive to TDP-43. In order to provide an early diagnosis and to conduct clinical trials for early treatment for ALS, it is crucial to fully understand muscle pathology in this condition. The study, entitled,…