In FUS-ALS Cell Model, Circular RNA ‘Trapped’ in Toxic Protein Clumps
Mutations in the FUS gene, which cause some forms of amyotrophic lateral sclerosis (ALS), result in a circular RNA…
Articles by Marisa Wexler, MS
London-based CERF Prizes Benefit U.S.-based Research
The Cullen Education and Research Fund (CERF), a private philanthropy based in London, has awarded more than $800,000 to support…
Structure of TDP-43 Protein Clumps Identified for First Time
A team of scientists in the U.K. and Japan has determined the structure of aggregated TDP-43, the protein whose abnormal clumps…
Oral Edaravone Under FDA Priority Review, Decision Expected in May
A decision is expected by May from the U.S. Food and Drug Administration (FDA) on an application seeking approval of…
Top 10 ALS Stories of 2021
ALS News Today brought you daily coverage of the latest scientific breakthroughs and clinical research related to amyotrophic…
Risk of ALS Increases Nearly Fourfold in NFL Players
Athletes who have played in the National Football League (NFL) are significantly more likely than the general population to develop…
Gene Therapy Targeting Motor Neurons in Brain May Help Treat ALS
While it’s long been believed that the death of motor neurons in the spinal cord is the main cause of…
Tau Protein in Alzheimer’s Linked to ALS Mitochondrial Dysfunction
An abnormal version of tau, a protein associated with Alzheimer’s disease, may contribute to the progression of amyotrophic lateral…
New Organoid May Allow for Deeper Study of Processes Leading to ALS
Using a new laboratory model of brain cells, researchers demonstrated that cells with mutations associated with amyotrophic lateral sclerosis…
Tofersen Fails to Slow SOD1-ALS in VALOR Trial, But Hopeful Trends Seen
Tofersen, an experimental treatment for amyotrophic lateral sclerosis (ALS) patients with mutations in the SOD1 gene, failed to significantly…