Possible Way Seen of Preventing Inflammation That Precedes ALS Onset
Toxic clumps due to the buildup of the TDP-43 protein can trigger the neuronal inflammation that precedes symptoms of amyotrophic lateral…
Articles by Marisa Wexler, MS
Telehealth ‘Helpful’ Alternative to In-person Care, Rare Disease Patients Say
A majority of rare disease patients using telehealth during the COVID-19 pandemic thought the experience positive, and many would like…
$2M NIH Grant Supports Work Into Cell Structures Linked to ALS Protein Clumps
A $2 million grant from the National Institutes of Health (NIH) is funding work to better understand how molecular…
Impaired RNA Quality Control May Underlie Neurodegeneration in People with C9orf72 Mutations
An impairment in the activity of the RNA exosome complex, which cells use to degrade defective RNA molecules, could contribute…
Study Describes New Compounds With Potential to Treat ALS
Newly developed compounds derived from ebselen could be used to treat some types of amyotrophic lateral sclerosis (ALS),…
C9orf72 Mutations Lead to Increased Immune Activity, Mouse Study Suggests
Mutations in the gene C9orf72, a common genetic cause of amyotrophic lateral sclerosis (ALS), cause immune cells to have…
ILB, Potential ALS Therapy in Phase 2 Trial,Named Orphan Drug in Europe
The European Commission has granted orphan drug designation to ILB, Tikomed‘s investigational treatment for amyotrophic…
Ultrasound Measures of Muscle May Help in Diagnosing, Evaluating ALS
Measurements taken of muscle using ultrasound could be useful in diagnosing or managing amyotrophic lateral sclerosis (ALS), a small study…
Study Finds Higher Risk of Prolonged Grief Among Bereaved Caregivers of MND Patients
Bereaved caregivers of people with motor neurone disease (MND) are at increased risk of prolonged grief disorder compared to the…
Diagnostic Delays in ALS ‘Surprisingly Large’ and Need Not Be, Study Says
Long delays between symptom onset and diagnosis are common with amyotrophic lateral sclerosis (ALS), and need not be if …