Anti-Inflammatory Delays ALS Symptoms and Progression in Mouse Model, Study Reports
Cromolyn sodium — a U.S. Food and Drug Administration (FDA)-approved anti-inflammatory medication — delayed disease onset and prevented…
Articles by Marta Figueiredo, PhD
1st ALS Patient Enters Phase 3 Study of Oral Edaravone in Slowing Disability
Mitsubishi Tanabe Pharma America (MTPA) has enrolled a first patient in a Phase 3 clinical trial of an oral…
AstroRx, ALS Cell Therapy, Shows Potential to Slow Progression, Early Trial Data Show
Kadimastem’s experimental cell therapy — AstroRx — may slow disease progression in patients with amyotrophic lateral sclerosis (ALS),…
Cannabis-based Sativex May Help Reduce Spasticity in ALS Patients, Study Suggests
Sativex, a cannabis-based product, may help ease spasticity (stiff muscles) in people with amyotrophic lateral sclerosis (ALS), a German real-world…
Gene Therapy Holds Promise to Treat ALS Caused by SOD1 Mutations, Preclinical Study Shows
An experimental gene therapy based on RNA interference (RNAi) shows potential to treat patients with familial amyotrophic lateral sclerosis…
Biohaven’s Under-the-Tongue BHV-0223 is One Step Closer to FDA Approval
The U.S. Food and Drug Administration (FDA) has accepted for review the new drug application (NDA) of Biohaven Pharmaceuticals’…
ALS-causative Mutations Directly Affect Sensory Nerves’ Growth and Stress Response, Preclinical Study Shows
Sensory nerves carrying mutations in the TDP-43 or SOD1 genes — associated with the development of a…
Prevalence of Motor Nerve Diseases, Including ALS, on Rise as Population Ages
The prevalence of motor nerve diseases — including amyotrophic lateral sclerosis (ALS) — is on the rise worldwide, mostly because…
Protein Clumps That Turn Toxic in ALS Also Found in Healthy Muscle Undergoing Repair, Study Reports
While TDP-43 aggregates are associated with amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases, researchers have found that these protein…
Stem Cell Therapy Safe in ALS Patients, Review Finds; Evaluating Effectiveness is Next
Stem cell therapy seems to be safe in patients with amyotrophic lateral sclerosis (ALS) and clinical trials evaluating its effectiveness…