Defects in Cell Cleanup System May Lead to ALS and Other Diseases, Mouse Study Shows
Researchers at Germany’s University of Würzburg have discovered how a malfunctioning autophagy – a cell’s natural self-degradation and cleanup system…
Articles by Patricia Inácio, PhD
Voyager Presents New Data in AAV Gene Therapy for ALS at European Conference
Voyager Therapeutics has recently presented data of its leading adeno-associated virus (AAV) gene therapy for several neurological diseases, including amyotrophic…
Human Skin Cells Successfully Converted into Motor Neurons
Scientists have discovered how adult skin cells can be converted into motor neurons without transitioning them through a stem cell…
AveXis and REGENXBIO Sign Licensing Agreement to Develop Therapies for ALS and Rett syndrome
AveXis and REGENXBIO have signed a new licensing agreement to develop therapies for a particular form of ALS and for…
Defective RNA Processing and Protein Folding May Promote ALS, Lab Study Suggests
Defects in RNA processing and transport, as well as protein folding, may contribute to amyotrophic lateral sclerosis (ALS) pathology, according to…
Protein in Cerebrospinal Fluid May Be Marker for ALS Therapy Success, Study Suggests
Scientists have found a potential protein biomarker in the cerebrospinal fluid of people carrying the most common mutation linked to amyotrophic lateral…
Electrodes Technique May Slow ALS Progression, Case Study Suggests
A single-case study of a patient with amyotrophic lateral sclerosis (ALS) suggests that long-term invasive motor cortex stimulation via implants of electrodes…
ALS Blood Inflammatory Markers Correlate with Disease Severity, Study Shows
An analysis of inflammatory marker levels in blood samples from amyotrophic lateral sclerosis (ALS) patients, improves patient categoration and may…
Specific Protein, P63, Seen to Promote ALS by Regulating Muscle Atrophy Effector Gene
In a new study, researchers found a protein in the p53 family, called p63, is increased in amyotrophic lateral sclerosis (ALS) and is a…
ALS Researchers Identify Loss of MHCI Protein as Key in Development of Disease
Researchers revealed that the loss of major histocompatibility complex I (MHCI) is a key step in the development of amyotrophic lateral…