Patrícia Silva, PhD, director of science content —

Researchers at Università degli Studi di Milano in Italy recently published in the journal Cells a review regarding the link between autophagy and amyotrophic lateral sclerosis (ALS). The study is entitled “Autophagy and Neurodegeneration: Insights from a Cultured Cell Model of ALS”. Autophagy…

Researchers at the University of Toronto and the Sunnybrook Health Sciences Centre in Canada recently reported the development of two new antibodies against a protein that plays a key role in amyotrophic lateral sclerosis (ALS) – C9ORF72. The study was published in the journal Annals…

Researchers at Ulm University and Eberhard Karls University in Germany recently developed a new in vitro model for the study of motor neuron diseases including amyotrophic lateral sclerosis (ALS). The study was published in the journal Stem Cell Research and is entitled “…

A study led by researchers at the National Institute of Neurological Disorders and Stroke (NINDS) recently published in the journal Neuron revealed new insights into why mutations in the SOD1 gene lead to the development of amyotrophic lateral sclerosis (ALS). The study is entitled “…

Researchers at the University of Massachusetts Medical School in the United States and the Babraham Institute in the United Kingdom recently revealed a new fly model to study motor neuron degeneration. The study was published in the journal Current Biology and is entitled “…

MediciNova, Inc., a biopharmaceutical company established in San Diego, recently announced in a press release that an abstract centered on the ongoing clinical trial evaluating the company’s product MN-166 (ibudilast) for amyotrophic lateral sclerosis (ALS) has been accepted for a presentation at the 26th International Symposium on…

A study led by researchers at The Center of Free Radical and Biomedical Research at Universidad de la Republica in Uruguay revealed that antioxidant therapies like MitoQ are a promising treatment strategy for amyotrophic lateral sclerosis (ALS). The study was published in the journal Free Radical Biology…

New data revealing a link between the LDL receptor-related protein 4 (LRP4) and amyotrophic lateral sclerosis (ALS) was presented during the 67th American Academy of Neurology Annual Meeting in April 2015. The presentation was entitled “LRP4 antibodies are frequent in serum and CSF from amyotrophic lateral sclerosis patients”. ALS is…

Researchers at the University of Alberta and the National Institute for Nanotechnology in Canada recently reported new insights into the misfolding process of proteins from a normal structure to a disease state characteristic of degenerative disorders. The study entitled “Protein misfolding occurs by slow diffusion…

Researchers at Columbia University, New York recently published in the journal Cell Reports their findings on eight different master regulators involved in amyotrophic lateral sclerosis (ALS) neurodegeneration in mouse models. The study is entitled “The Regulatory Machinery of Neurodegeneration in In Vitro Models…