New research points to evidence that physical fitness, body mass index (BMI), IQ, and stress resilience in young adults might play a role in the development of amyotrophic lateral sclerosis (ALS). The study, “Physical and cognitive fitness in young adulthood and risk of amyotrophic lateral sclerosis at an…
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Incorporating music therapy into standard treatments for amyotrophic lateral sclerosis (ALS) patients may improve the patient’s quality of life, according to new research. The study, “Active Music Therapy Approach In Amyotrophic Lateral Sclerosis: A Randomized-Controlled Trial,” was published in the International Journal of Rehabilitation Research. “[T]he sonorous-music and…
Researchers have identified several new variants in genes associated with amyotrophic lateral sclerosis (ALS), many in patients with no history of the disease in their family. The study, “Rare Variants In Neurodegeneration Associated Genes Revealed By Targeted Panel Sequencing In A German ALS Cohort,” was published in the journal Frontiers…
Mutations in a gene called SOD1 lead to the development of cellular anomalies associated with amyotrophic lateral sclerosis (ALS), according to a new study using animal models of the disease. Such anomalies included deficient regulation of amino acid levels, which are crucial for protein production and cell activity, but could…
Repeated head injury can cause brain inflammation that triggers the development of chronic traumatic encephalopathy — a condition that has been linked to several neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). The study, “Microglial neuroinflammation contributes to tau accumulation in chronic traumatic encephalopathy,” was published in the…
A report in the journal Experimental Neurobiology reviewed the role of astrocytes (cells that support and protect neurons) and microglia (immune system cells in the brain) in amyotrophic lateral sclerosis (ALS). The authors, from the Veterans Affairs Boston Healthcare System; the Department of Neurology at Boston University School of Medicine;…
Smoking contributes to disease progression in amyotrophic lateral sclerosis (ALS) and decreases patient survival by about two years regardless of age, gender, or other disease modifiers such as respiratory function, chronic obstructive pulmonary disease (COPD) and ALS-associated gene mutations, according to new research. These findings suggest that neurologists should advise…
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Neuroimaging Techniques Confirm Neuropathological Findings that Contribute to Degeneration in ALS
Advanced neuroimaging techniques and neuropsychological evaluations of patients with amyotrophic lateral sclerosis (ALS) recently confirmed the existence of a unique micro-structural brain degeneration pattern that contributes to memory loss, according to a study conducted by an international research team that included a group from Baylor College of Medicine. The report, “…
Diets rich in fruits and vegetables may be associated with better function, including respiratory, in amyotrophic lateral sclerosis (ALS), according to a new study. The study, “Association Between Dietary Intake and Function in Amyotrophic Lateral Sclerosis”, was published in the journal JAMA Neurology. “There is growing interest in…
Regenerative medicine investigators at the Cedars-Sinai Medical Center have received U.S. Food and Drug Administration (FDA) approval to test a novel combination stem cell-gene therapy they’ve developed to stall amyotrophic lateral sclerosis (ALS) progression. Enrollment in the trial is expected to commence soon. Also known as Lou Gehrig’s disease, ALS is…
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