Stem cell therapies are generally safe and well tolerated in people with amyotrophic lateral sclerosis (ALS), and preliminary evidence from clinical trials suggests they may also help slow functional decline, according to a systematic review and meta-analysis of several published studies. Researchers found that people given stem cell therapies…
Stem cell therapy may slow ALS functional decline, researchers say
Loneliness and regret are key drivers of mental health distress among people with amyotrophic lateral sclerosis (ALS), according to a new survey — but the researchers also found that maintaining a hopeful outlook may help those with the rare disease to combat anxiety, depression, and frustration. The survey,…
Researchers, physicians, industry partners, caregivers, and people with amyotrophic lateral sclerosis (ALS) are gearing up to gather for the third annual ALS Nexus conference, an effort from the ALS Association to bring the ALS community together around a shared goal of changing the future of ALS. The…
I’m writing this column from one of my favorite places with two of my most beloved people. It’s an overcast morning here at my little creek house on the eastern shore of Maryland, and I’m nestled in a rocking chair with a cup of black coffee, something I would’ve done…
People with amyotrophic lateral sclerosis (ALS) who have a history of strenuous exercise tend to develop the disease earlier than patients who were less physically active, according to a study. However, data showed that heavy exercise does not increase the risk of death for ALS patients, and exercise itself…
Analyses of vocal recordings using artificial intelligence (AI) may aid in the diagnosis of amyotrophic lateral sclerosis (ALS), particularly among those with a form of the disease called bulbar-onset ALS that initially affects the mouth and throat, a new study suggests. Bulbar-onset ALS generally has a poorer prognosis than…
I planned an end-of-summer trip to spend time with my daughter and friends near Milwaukee, Wisconsin, where my husband, Todd, and I lived when he was diagnosed with ALS 16 years ago. I needed time away from being constantly on duty. The trip also gave me a new perspective…
New analyses of data from two Phase 2 clinical trials and observational studies suggest that changes in blood levels of neurofilament light chain (NfL), a biomarker of nerve damage, may help predict which people with amyotrophic lateral sclerosis (ALS) are more likely to experience clinical benefits with Clene’s…
Neurosense Therapeutics plans to seek Health Canada approval by the end of the year for PrimeC, its experimental oral therapy for amyotrophic lateral sclerosis (ALS). The planned new drug submission (NDS) filing follows completion of a pre-NDS process and finalization of the related meeting minutes. The process is…
People whose jobs expose them to pesticides may be more likely to develop amyotrophic lateral sclerosis (ALS) than workers who aren’t exposed, according to a systematic review and meta-analysis. Researchers found that occupational pesticide exposure was associated with a higher risk of developing ALS. Among different pesticide classes, exposure…
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