Promising findings seen in healthy volunteer study of Axoltis’ NX210c

Axoltis Pharma‘s new treatment candidate for amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases was deemed safe and well tolerated at multiple doses in healthy volunteers who participated in a Phase 1b trial. Findings from the trial and preclinical studies also indicate NX210c is working as intended, boosting…

Throughout 2023, ALS News Today brought you daily coverage of the latest clinical research and scientific breakthroughs related to amyotrophic lateral sclerosis (ALS). Here are the year’s top 10 most-read articles, each with a brief description. We’re excited to remain a dependable resource for the ALS community in…

I’m not a big believer in making New Year’s resolutions. There’s something that feels bad about setting a goal that’s lofty — learning a new language is one of my perennial favorites, for example — and then not accomplishing it. Plus, I keep a daily to-do list that includes some…

Exposure to certain toxic airborne chemicals used in industry significantly increases — by up to six times — the odds of developing amyotrophic lateral sclerosis (ALS), a study suggests. Findings underscore the importance of surveillance programs testing exposure to these airborne pollutants, especially among populations at risk. The study,…

Transcranial stimulation — a noninvasive technique that delivers low electrical currents to the brain to fine-tune nerve cell activity — improved muscle strength and quality of life in people with amyotrophic lateral sclerosis (ALS) in a small clinical trial. Researchers also found that a two-week course of transcranial direct…

People with negative responses to a tuberculin skin test a few years after being vaccinated against tuberculosis had a significant, 25% lower risk of developing amyotrophic lateral sclerosis (ALS) in their lifetime, according to a study in Norway. Because a positive reaction is linked to the recruitment of T…

Is anyone else bombarded by social media messages to set goals, make New Year’s resolutions, or create a bucket list for 2024? I sure have been. In my pre-ALS days, I heeded the reminders. I looked forward to breaking in a brand-new desk calendar and filling it with my…

Accidents can and will happen. Do you have a plan for when they do? The two accidents I’ve feared the most since being debilitated with ALS are getting scalded in the shower and smashing my toes against the wall or any other object when I’m in my wheelchair. I…

Early data from Phase 2 programs showing that CNM-Au8, an oral therapy candidate for amyotrophic lateral sclerosis (ALS), induced significant reductions in a nerve damage biomarker but did not meet the criteria for accelerated approval at this time, the U.S. Food and Drug Administration (FDA) concluded. Despite the…

After I finished this holiday season’s wreath orders, I moved my wreath-making table out of the dining room back into the garage and put away extra pine cones, bows, and birch bark. The room felt spacious without the clutter, and I told my husband, Todd, “This reminds me of the…