Researchers have developed a method to measure the effectiveness of a process of RNA destruction that clears abnormal molecules from cells. Since abnormally high production of junk RNA has been thought to contribute to amyotrophic lateral sclerosis (ALS), the method can be used to screen for drugs that may boost…

Research into patients with amyotrophic lateral sclerosis (ALS) has found that the eye muscles are not affected by the disease that attacks all the other muscles in the body. Researchers focus on eye and limb muscles for clues about the disease. Read more here.  The Swedish study found that even…

The fitness franchise Orangetheory Fitness has partnered with Augie’s Quest to raise $1 million over the next two weeks for amyotrophic lateral sclerosis (ALS) research. During the campaign (#IBurnForALS) — which lasts from February 20 to March 5 — more than 570 Orangetheory studios nationwide will encourage their members…

A recent study has found that low levels of vitamin D are linked to loss of movement in amyotrophic lateral sclerosis (ALS). However, lower levels of the vitamin were not to blame for the progression of symptoms. Learn more about the molecular changes in ALS in this video.   In…

If parents pass on mutations in the C9orf72 gene, their children not only develop amyotrophic lateral sclerosis (ALS) or frontotemporal dementia but do so at an earlier age due to an expansion of the mutation. This finding makes it easier for physicians to determine when to start monitoring an individual carrying a C9orf72…

Two French researchers, Martine Barkats and Maria-Grazia Biferi, are winners of the Avi Kremer ALS Treatment Prize, worth $1 million, for developing a gene therapy approach that shows promise in treating certain types of amyotrophic lateral sclerosis (ALS), Prize4Life announced in a recent press release. The approach targets one of the…

Neuraltus Pharmaceuticals has enrolled 50 of the 120 patients it hopes to obtain for a confirmatory Phase 2 clinical trial evaluating NP001 as a treatment for amyotrophic lateral sclerosis (ALS). Completion of enrollment is expected in mid-2017, with Neuraltus shooting for results in early 2018. Eighteen clinical sites across North…

In this video, Bernardo Pinto Coelho talks about his journey with amyotrophic lateral sclerosis (ALS), explains his five rules for life and discusses how radically changing his diet brought about a change in his ALS symptoms.

Researchers have developed a molecule called 123C4 that targets the EphA4 receptor, which is known to contribute to the development of amyotrophic lateral sclerosis (ALS), according to a new study. The paper, “Potent and Selective Epha4 Agonists for the Treatment of ALS,” appeared in the journal Cell Chemical Biology. Its…

Swiss drugmaker GeNeuro has signed an agreement with the National Institute of Neurological Disorders and Stroke (NINDS) — part of the U.S. National Institutes of Health (NIH) — to advance studies of its novel therapeutic antibodies for the treatment of amyotrophic lateral sclerosis (ALS). Under the Cooperative Research and Development Agreement, GeNeuro will…