Activity seen in two of the brain’s resting state networks in amyotrophic lateral sclerosis (ALS) patients may be a sign of more severe and rapidly progressing disease in a person. These networks, at work when a person is not focusing on a specific task, were investigated in the study, “Investigating Default Mode and…

An analysis of inflammatory marker levels in blood samples from amyotrophic lateral sclerosis (ALS) patients, improves patient categoration and may help design future ALS clinical trials, according to a new study. The study “Systemic inflammatory response and neuromuscular involvement in amyotrophic lateral sclerosis,” was published in the journal…

Target ALS Foundation, focused on finding new treatments for amyotrophic lateral sclerosis (ALS), has selected RUCDR Infinite Biologics as the biorepository for banking and distributing the foundation’s human stem cell lines to be used in industry and research. The privately funded non-profit institution, funds consortia-based collaborative projects that aim to decrease obstacles…

A group of women in their 60s decided to go full Monty to raise awareness for amyotrophic lateral sclerosis (ALS). The idea came from lifelong friends of Wendy Rauwerdink of Sheboygan, Wisconsin, who had diagnosed with the disease. Her friends became engaged in the fight, always wanting to do more.

Researchers reviewed both current and emerging technical approaches that show the most promise in the detection of upper motor neuron (UMN) degeneration of ALS patients. By assessing and comparing the utility of cutting-edge imaging and electrophysiological approaches, researchers hope to identify biomarkers for UMN dysfunction that can serve as early diagnostics for…

“Die Trying”, this Friday’s episode of HBO’s edgy half-hour newsmagazine series VICE, is about ALS and hosted by the show’s Senior Associate Editor Angelina Fanous who is battling the disease. A preview trailer can be viewed at: https://als.vice.com/. Living with ALS, Egyptian-born Fanous is now focusing on…

Amyotrophic lateral sclerosis (ALS) is a disease that progressively shuts down your muscles by attacking certain cells in the brain and spinal cord needed to keep our muscles moving. Eventually, patients will lose their mobility, have trouble moving, walking, swallowing and even breathing. There is no known cure for ALS…

Researchers at the Karolinska Institute in Sweden and the University of Barcelona in Spain studied the contribution of cellular redox environment changes to the stability and integrity of SOD1, a protein implicated in the development and progression of familial amyotrophic lateral sclerosis (ALS). A key finding was that mutations in the…

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord. ALS usually affects people between the ages of 40 and 70, but this doesn’t mean that it cannot be diagnosed at other ages. Unfortunately, around 20,000 American citizens are estimated to develop the disease…

Researchers at the University of California-Riverside have shown, for the first time, that infection from the common parasite Toxoplasma gondii disrupts neurotransmitter glutamate function in the brain, potentially leading to neuronal death and neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS), in individuals predisposed to such conditions. The research paper, “…