According to a recent study published in the journal JAMA Neurology, type 2 diabetes is associated with a diminished risk of amyotrophic lateral sclerosis (ALS). The study revealed that the risk is directly associated with the age at diagnosis of diabetes and the age at diagnosis of…
A neural prosthetic device surgically implanted in Erik G. Sorto, 34, left quadriplegic by gunshot wound 13 years ago, has enabled the single father of two to now move a robotic arm via only thought input. This major breakthrough is the outcome of a clinical collaboration between The California Institute…
AB Science SA, a pharmaceutical company focused on research, development and marketing of protein kinase inhibitors (PKIs), has announced that it is hosting a web conference including key opinion leaders and experts covering its experimental therapy masitinib and its utility to treat amyotrophic lateral sclerosis (ALS). The web conference call will be held from 5:35…
A new study recently published in the journal Acta Neuropathologica Communications revealed that the absence of the FUS/TLS protein, which has been linked to neurological diseases, causes symptoms distinct from the ones found in amyotrophic lateral sclerosis (ALS) patients. The study is entitled “FUS/TLS…
To better understand amyotrophic lateral sclerosis (ALS), a research team at Johns Hopkins Medicine was able to transform skin cells from ALS and Lou Gehrig’s disease patients into brain cells affected by this severe condition. The researchers deposited the human-made cells derived from the study into the first…
A study published in the latest edition of Nature Immunology presents evidence that a key protein associated with Amyotrophic lateral sclerosis (ALS) also plays an important role in a patient’s immune response to viral infections. The study entitled, “Senataxin suppresses the antiviral transcriptional…
In a recent study titled “Senataxin suppresses the antiviral transcriptional response and controls viral biogenesis,” published in the journal Nature Immunology, researchers at Mount Sinai Hospital/Mount Sinai School of Medicine found that a human protein called senataxin (SETX), which has been found to…
Researchers at the Second University of Naples and the University of Parma in Italy recently characterized the microstructural brain alterations in patients with amyotrophic lateral sclerosis (ALS) during disease progression. The findings were published in the journal PLoS ONE and the study is entitled…
A research team at Penn Medicine recently found that hypermethylation is able to inhibit the development of Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Degeneration (FTD) in a study titled, “C9orf72 promoter hypermethylation is neuroprotective: Neuroimaging and neuropathologic evidence.” The results are published in the journal…
Results from a recent Phase I clinical trial in patients with Amyotrophic Lateral Sclerosis (ALS) showed a safe cell therapy approach that may allow for the treatment of larger pools of patients for later-phase ALS trials. The study is published in the Journal of Translational Medicine.
