Showing 4140 results for "als"

Some caregiving tips apply to more than ALS

A couple days ago, as I was dishing up our family dinner, I popped a piece of chicken in my mouth and accidentally aspirated, drawing a small piece of chicken or phlegm into my lungs. I tried to cough it up, but wasn’t getting it out. I winced and pounded…

ALS/MND 2023: AMX0114 may enter clinical testing next year

Amylyx Pharmaceuticals is developing AMX0114, a new experimental treatment for amyotrophic lateral sclerosis (ALS) that’s designed to promote the health of nerve fibers by lowering levels of calpain-2, a protein. AMX0114 is being tested in preclinical studies with the aim of supporting an investigational new drug application (IND),…

My new ALS management strategy is to give myself a mission

As much as I’d love to be perceived as an I’ve-got-it-all-figured-out sort of ALS patient, I’m not. I have to invent mental strategies all the time to help me navigate through my day. Lately, I’ve been easily distracted and not paying attention to what I’m doing. Only then will…

Final part of Phase 1 trial to test prosetin in ALS patients

Health Canada has cleared ProJenX to open the third part of its ongoing Phase 1 clinical trial and begin testing the experimental therapy prosetin in people with amyotrophic lateral sclerosis (ALS). The first two parts of the PRO-101 trial (NCT05279755) involved healthy participants and showed that the…

Blink reflex test may be biomarker to diagnose, monitor ALS: Study

A test that assesses the electrical activity associated with blinking may help speed the diagnosis of amyotrophic lateral sclerosis (ALS) and monitor disease progression in people with the condition, a study found. Findings showed that certain electrical waves can significantly distinguish people with ALS from healthy controls or…

ALS symptoms: Difficulty breathing and swallowing

Amyotrophic lateral sclerosis (ALS) is a progressive, neurodegenerative disease that affects the muscles involved in swallowing and breathing, potentially leading to issues such as malnutrition and weight loss, along with aspiration and lung infections.