BrainStorm Cell Therapeutics has signed an agreement with the University of California Irvine Medical Center (UCI) to start enrolling patients for an upcoming Phase 3 clinical trial evaluating whether NurOwn can improve functional impairment in amyotrophic lateral sclerosis (ALS) patients. NurOwn is made of mesenchymal stem cells…

Actor, director and playwright, Sam Shepard, has died following a battle with amyotrophic lateral sclerosis (ALS). The star passed away at his Kentucky home on Thursday, July 27, surrounded by his family following a lengthy and private battle with the disease. MORE: Explaining amyotrophic lateral sclerosis (ALS) As a Hollywood…

Healthcare providers may now begin researching the insurance benefits process for patients in advance of the upcoming availability of Radicava (edaravone), an approved treatment for amyotrophic lateral sclerosis (ALS), according to the therapy’s distributor in the U.S., Mitsubishi Tanabe Pharma America. The U.S. Food and Drug Administration (FDA)…

Cytokinetics recently announced the start of a Phase 2 clinical trial investigating a new therapy candidate (CK-2127107) for the potential treatment of amyotrophic lateral sclerosis (ALS). The Phase 2 FORTITUDE-ALS (NCT03160898) study will soon be…

We know dealing with amyotrophic lateral sclerosis (ALS) sometimes feels like an uphill battle, both for the patients and the caregivers. You feel like you’re not doing enough or as if the disease is taking up all your time and attention. To help you on your journey, we’ve gathered a few quotes we thought…

Scientists have known for some time that abnormal DNA repetitions in the C9orf72 gene contribute to neuron death in ALS and frontotemporal dementia. Now they have learned how it happens: The anomalies leave DNA susceptible to damage, prompting a cell repair mechanism to become over-active. That hyperactivity cause neuron deaths.

This video from WCVB Channel 5 Boston is all about Rick Marks from Winchester, Massachusetts. Following an amyotrophic lateral sclerosis (ALS) diagnosis last October at the age of 55, Marks decided to raise awareness of the disease by hiking from Massachusetts to Maine. MORE: TV presenter talks about…

Researchers have discovered a natural mechanism that can help prevent the formation of harmful protein clumps that contribute to the development of amyotrophic lateral sclerosis (ALS), according to results of a new study. They also gained new insights into the formation of the protein clumps known as TDP-43 protein aggregates that…

RNA molecules that are not supposed to leave the cell nucleus might be responsible for driving neuronal cell death in people with amyotrophic lateral sclerosis (ALS), researchers from England’s University of Sheffield report in a study that suggests a way to prevent that from happening. The research team discovered just how…

This video from Alisa Apreleva is all about an awareness campaign in Moscow, Russia, that’s helping to highlight amyotrophic lateral sclerosis (ALS). MORE: What research is being done on ALS? The video features Russian recording artists and patients in various stages of the disease singing a specially written and composed…