In a recent study entitled “ALS-Linked P56S-VAPB Mutation Impairs the Formation of Multinuclear Myotube in C2C12 Cells” researchers investigated the role of a mutation associated with ALS type-8 (ALS8) – P56S-VAPB mutation – on skeletal muscle cells homeostasis and muscle formation. The study was published in the…
A study led by researchers at the National Institute of Neurological Disorders and Stroke (NINDS) recently published in the journal Neuron revealed new insights into why mutations in the SOD1 gene lead to the development of amyotrophic lateral sclerosis (ALS). The study is entitled “…
The ALS Therapy Development Institute has just signed a research partnership with Chaperone Therapeutics, Inc., a company that specializes in treatments that address protein misfolding and neuronal cell loss, the underlying causes of neurodegenerative disease. The new partners will be working on potential treatments for amyotrophic lateral sclerosis (ALS), in order to facilitate preclinical development…
Researchers at the University of Massachusetts Medical School in the United States and the Babraham Institute in the United Kingdom recently revealed a new fly model to study motor neuron degeneration. The study was published in the journal Current Biology and is entitled “…
One of the country’s most accomplished professors of neurosurgery, neural and behavioral sciences and pediatrics at Penn State College of Medicine, James Connor, has just received a three-year grant worth $240,000 from the ALS Society to support his work on a nutrition-based solution that can be given via pain-medication delivery…
It has already been a year since the ALS Ice Bucket Challenge took the internet by storm, causing countless American households, celebrities and public figures to show support for ongoing efforts to find a cure for amyotrophic lateral sclerosis. In the wake of the viral campaign, a team of scientists…
Biopharmaceutical company, Neuralstem, Inc. has just announced the US District Court in Maryland has decided to dismiss StemCell, Inc.’s previously filed patent infringement case with prejudice in StemCells, Inc. v. Neuralstem, Inc. in favor of Neuralstem, on July 22, 2015. Neuralstem is most known for its proprietary stem cell technology. It has…
MediciNova, Inc., a biopharmaceutical company established in San Diego, recently announced in a press release that an abstract centered on the ongoing clinical trial evaluating the company’s product MN-166 (ibudilast) for amyotrophic lateral sclerosis (ALS) has been accepted for a presentation at the 26th International Symposium on…
Last year a monumental push to increase research funding for Amyotrophic Lateral Sclerosis (ALS), known as the ALS Ice Bucket Challenge, raised over $220 million globally for ALS research and patient care. The video based social media challenge is set to return this year beginning July 31st. Co-founder Pat…
Amyotrophic lateral sclerosis (ALS) is a disease that involves the death of neurons that activate voluntary muscles. These muscles are called skeletal striated muscles and are responsible for our ability to walk, talk and even breathe. The disease, also known as Lou Gehrig’s or Charcot disease, is therefore characterized by stiff muscles, muscle twitching and…
