Researchers homed in on how a particular protein, called semaphorin 3A (Sema3A), affects the survival of motor neurons in both the brain and spinal cord in models of amyotrophic lateral sclerosis (ALS). Their study, “ALS-related human cortical and motor neurons survival is differentially affected by Sema3A,” appeared in the…

Interleukin 4 reduces the severity of clinical symptoms during the early phase of amyotrophic lateral sclerosis (ALS), but has no effect in halting the death of motor neuron cells as ALS progresses, an Italian mouse study shows. The study, “Interleukin 4 modulates microglia homeostasis and attenuates the early slowly…

Orangetheory fitness members across the United States and Canada plan to raise $2 million for Augie’s Quest to cure ALS, an organization supporting research into a cure for amyotrophic lateral sclerosis (ALS). Money raised this year will go to help advance a promising potential ALS treatment, AT-1501,…

In this video from CBS Sunday Morning, follow the journey of award-winning filmmaker Simon Fitzmaurice as he completes his pet project, a film called My Name is Emily, despite being diagnosed with amyotrophic lateral sclerosis (ALS) eight years ago. MORE: Explaining the progression…

The amount of RNA molecules present in the blood and central nervous system of amyotrophic lateral sclerosis (ALS) patients seems to play a role in the onset and development of the disease, a study published in the journal Scientific Reports showed. A better understanding of the involvement of RNA molecules…

Researchers in Germany studying standards of care in amyotrophic lateral sclerosis (ALS) patients found a high unmet need for assistive technology devices. The cohort study, “Provision of assistive technology devices among people with ALS in Germany: a platform-case management approach,” was published in the journal Amyotrophic Lateral Sclerosis and…

Researchers at Sweden’s University of Gothenburg say low red blood cell count at a young age is a risk factor for amyotrophic lateral sclerosis (ALS). Disease onset was also associated with low muscle strength and low body fat during the later teen years. ”One should never overstate conclusions from a…

https://vimeo.com/124559355 This video from the ALS Association Texas chapter is all about a talented young artist, Alexis. Alexis has loved drawing since she was a child, but the progression of her amyotrophic lateral sclerosis (ALS) condition has meant that she can now no longer draw with paper and pencils. However, she hasn’t let…

Neurodegeneration in a subset of amyotrophic lateral sclerosis (ALS) patients is a consequence of abnormal DNA damage responses, a finding that provides new possibilities for therapeutic interventions. About 5 percent of familial amyotrophic lateral sclerosis (fALS), and up to 1 percent of sporadic ALS (sALS), have been linked to mutations in…

The higher the levels of uric acid in the blood of amyotrophic lateral sclerosis (ALS) patients, the lower the risk of death from all causes, a study found. The body produces uric acid when it breaks down purines, which are substances both normally produced and found in certain…