Could This Newly Developed Molecule Treat ALS?

Scientists have developed a new molecule which has the potential to treat patients with amyotrophic lateral sclerosis (ALS).

Find out more about the molecular changes that occur in ALS.

Researchers had previously identified the EphA4 receptor as playing an important role in the development of many diseases including ALS, Alzheimer’s disease, and some gastrointestinal cancers.

The new 123C4 molecule was seen to target and block the EphA4 receptor in mouse models by binding to them and removing them from the surface of the neurons. This slowed down the progression of ALS in the mice.

The study still has much work ahead to determine whether the 1234C molecule can be used in any therapeutic way for ALS patients, but scientists are hopeful that this is the first step in the right direction. Find out more about this study here. 

Find out more about clinical trials for ALS here. 

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