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April 14, 2022 News by Lindsey Shapiro, PhD

Blocking Astrocyte Protein May Slow ALS Progression, Study Finds

Blocking channels containing the connexin 43 (Cx43) protein on astrocytes — a type of nerve support cell — slowed disease progression in a mouse model of amyotrophic lateral sclerosis (ALS), a study found. The protein was found to be increased in ALS patient tissues and spinal fluid, and its…

April 29, 2020 News by Inês Martins, PhD

Reducing Excess Firing of Motor Neurons Delays Symptoms in Animal Model of ALS

Reducing the excess firing of motor neurons in an animal model of amyotrophic lateral sclerosis (ALS) prevents the death of nerve cells and significantly delays the onset of motor symptoms, a recent study has found. Because the scientific approach made use of two techniques that have been studied extensively…

April 5, 2019 News by José Lopes, PhD

Transplanted Human Bone Marrow Cells Hold Promise as ALS Therapy, Mouse Study Shows

Transplanting certain human bone marrow cells into mice with amyotrophic lateral sclerosis (ALS) improved their motor function and preserved motor neurons by repairing the barrier protecting the spinal cord. The study with that finding, “Human Bone Marrow Endothelial Progenitor Cell Transplantation into Symptomatic ALS Mice Delays Disease…

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