Do ALS symptoms come and go?

Amyotrophic lateral sclerosis (ALS) is a progressive disorder, meaning symptoms continually get worse as time goes on. This progression isn’t usually a straight line — symptoms may rapidly worsen for a time, then stay mostly stable for a while before deteriorating again. Patients may experience some day-to-day variability in their experiences of symptoms, and there may even be times when some lost functionality is recovered, but such periods are almost always temporary and patients will eventually experience continued symptom worsening.