The National Institute of Neurological Disorders and Stroke (NINDS) is one of the world’s leading funders of research into amyotrophic lateral sclerosis (ALS). Its goals are to better understand the cellular mechanisms which lead to the development and subsequent progression of ALS, discover more about the genetics and risk factors associated with the disease, identify biomarkers, and to develop and improve treatments.
Some of the current research programs for ALS include looking into what causes motor neuron cell death, the use of stem cells as possible treatments, comparing familial and sporadic ALS cases to identify genes involved in the development of the disease, discovering new biomarkers to improve the way the disease is diagnosed in patients, and new treatments and therapies including drugs, stem-cell therapy, antibodies, and gene therapies.
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