CannTrust Partnering with Australian Hospital for Trial Testing Cannabidiol Capsules for ALS

CannTrust Partnering with Australian Hospital for Trial Testing Cannabidiol Capsules for ALS

CannTrust is getting ready to launch a clinical trial to assess the effectiveness of its cannabidiol (CBD) oil capsules on slowing the progression of amyotrophic lateral sclerosis (ALS) and other motor neuron diseases (MNDs).

This new study is the result of a collaboration between Canada-based CannTrust and Gold Coast University Hospital, one of the leading tertiary referral institutions in Australia for ALS management.

“This study will help advance our understanding of the potential effects of CannTrust’s standardized CBD oil capsules on ALS/MND, both as a disease modifying agent and as a symptomatic treatment and will become the basis for conducting future cannabinoid and ALS clinical trials,” Arman Sabet, MD, a neurologist at Gold Coast University Hospital and the lead researcher of the study, said in a press release.

The randomized, double-blind, placebo-controlled study will assign participants to receive either CannTrust’s standardized CBD oil capsules or a placebo for about six months.

Researchers will evaluate the effects of the treatment on disease manifestations including pain, weight loss, and muscle contraction (spasticity), as well as its impact on patients’ quality of life and the therapy’s potential to prevent motor function decline in patients with ALS and MND. They will also assess the incidence of treatment-related adverse events and its tolerability profile.

The study has received research ethics board approval and Australian Therapeutic Goods Administration acknowledgement for the therapy, which are regulatory requirements that guarantee the safety of the participants.

“The rate of ALS progression is often rapid, creating high levels of disability for patients. People diagnosed with ALS have an average life expectancy of 2.5 years,” said Eric Paul, CEO of CannTrust. “CannTrust is proud to participate in this important study which aims to help us better understand the potential impact of CannTrust CBD oil capsules on ALS and MND, so that patients might face better outcomes.”

CBD is one of the more than 100 pharmacologically active compounds (cannabinoids) that can be retrieved from the cannabis plant. Studies have suggested it can modulate spasticity, as well manage seizures, inflammation, pain, anxiety, and other conditions.

Studies have demonstrated that cannabinoids have neuroprotective activity in animal models of ALS, and they can delay disease progression and prolong survival of the animals. Few studies have investigated the effect of cannabinoids in humans, which makes it difficult to fully understand its effects.

Because it does not have the psychoactive properties common to other cannabis-related compounds, CBD holds greater therapeutic potential. Still, it has been linked to some adverse side effects, such as drowsiness, decreased appetite, diarrhea, fatigue, and convulsions.

10 comments

  1. Tim says:

    its about time! I have been taking it for a few months now. it eases my muscle spasms, sleep better, helps with anxiety and some pain too.

  2. Charlie says:

    Looks like a placebo. It makes the user feel better, but it doesn’t affect the illness.

    It reminds me of Lunasin.

    The Skripals and two others were poisoned by a nerve agent. The basic molecules of nerve-agents are organo-phosphates. Agriculture land run-offs are full fertiliser run-offs which contain some organo-phosphates derivatives already linked to ALS.

    Researchers dare not look at this as the Monsanto legal team, and others, would ruin their careers. This area has more potential for finding the cause but research simply looks to find something to ‘slow things down’ and find a ‘treatment, not a cure.’

    Research is looking in the WRONG place.

  3. Alfredo Aiello says:

    My name is Alfredo Aiello from woodbridge Ontario Canada, I have als for 4 years I been taking cbd before do you think this cbd capsules is going to help me. please reply, thank you.

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