Posts by: Alice Melão

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The non-invasive delivery of ultrasound waves in a controlled, targeted manner can be safely used to open the blood-brain barrier in people with amyotrophic lateral sclerosis (ALS), giving temporary ... Read more

November 5, 2019

Canada Approves New Patent Covering Ibudilast’s Use for ALS Treatment

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The Canadian Intellectual Property Office has approved a new patent application that will allow MediciNova to use its investigational therapy ibudilast (MN-166) for the treatment of patients with amyotrophic lateral ... Read more

October 30, 2019October 30, 2019

First ALS Patient Enters US Study of Radicava’s Impact on Disease Biomarkers

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The REFINE-ALS study, an effort to identify and measure the levels of specific biomarkers in amyotrophic lateral sclerosis (ALS) patients being treated for a first time with Radicava (edaravone), has enrolled its ... Read more

October 9, 2019October 9, 2019

CENTAUR Phase 2 Trial of AMX0035, Potential ALS Treatment, Finishes Collecting Data

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The final amyotrophic lateral sclerosis (ALS) patient treated with oral AMX0035 in the CENTAUR study has completed all scheduled follow-up visits and researchers will now evaluate data collected on the ... Read more

September 30, 2019October 2, 2019

Mitochondria Play a Critical Role in Neuroinflammation, Neuron Cell Death, Study Reveals

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The release of fragmented or dysfunctional mitochondria — a cell’s powerhouse — by immune and structural cells inside the central nervous system is a critical step that triggers neuron ... Read more

September 26, 2019September 26, 2019

New Study Sheds Light on How Electrical Signals Control, Maintain Muscle Movement

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A detailed analysis of the communication network between nerve and muscle cells in turtles has shed new light on how movement is controlled and maintained. These findings on how ... Read more

September 6, 2019September 11, 2019

Researchers Uncover HSP90 Mechanism That May Help Explain Motor Nerve Death

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A new molecular mechanism that contributes to the death of some nerve cells has been discovered by a team of scientists led by researchers at Oregon State University. The ... Read more

August 7, 2019August 26, 2019

Underweight ALS Patients at Risk for Poorer Outcomes at Later Stages of Disease, Study Suggests

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Being underweight when they start supported feeding puts patients with amyotrophic lateral sclerosis (ALS) at risk for poor outcomes at later stages of the disease, an Italian study has ... Read more

August 5, 2019August 27, 2019

ALS Patients Have Impaired Connectivity in Certain Brain Regions, Study Suggests

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Amyotrophic lateral sclerosis (ALS) is characterized by specific changes in brain activity and connectivity, which are associated with motor and cognitive symptoms, an international research team has found. Therefore, ... Read more

July 16, 2019August 8, 2019

Enrollment Completed for Phase 3 REFALS Trial Evaluating Levosimendan in ALS Patients

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The Phase 3 REFALS trial exploring the impact of oral levosimendan (ODM-109) in patients with amyotrophic lateral sclerosis (ALS) has completed its target enrollment, the therapy’s manufacturer, Orion, announced. ... Read more

Posts by: Alice Melão

Alice Melão

MRI-guided Focused Ultrasounds Can Safely Open Brain-Blood Barrier in ALS Patients, Trial Shows

Canada Approves New Patent Covering Ibudilast’s Use for ALS Treatment

First ALS Patient Enters US Study of Radicava’s Impact on Disease Biomarkers

CENTAUR Phase 2 Trial of AMX0035, Potential ALS Treatment, Finishes Collecting Data

Mitochondria Play a Critical Role in Neuroinflammation, Neuron Cell Death, Study Reveals

New Study Sheds Light on How Electrical Signals Control, Maintain Muscle Movement

Researchers Uncover HSP90 Mechanism That May Help Explain Motor Nerve Death

Underweight ALS Patients at Risk for Poorer Outcomes at Later Stages of Disease, Study Suggests

ALS Patients Have Impaired Connectivity in Certain Brain Regions, Study Suggests

Enrollment Completed for Phase 3 REFALS Trial Evaluating Levosimendan in ALS Patients

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