Posts by: Alice Melão

News

The U.S. Food and Drug Administration (FDA) granted Orphan Drug Designation to Revalesio’s investigational drug RNS60 to treat amyotrophic lateral sclerosis (ALS). The status gives incentives for companies to develop new therapies ... Read more

September 21, 2017September 24, 2017

FDA Grants Orphan Drug Status to Amylyx’s AMX0035 for Treatment of ALS

News

The U.S. Food and Drug Administration (FDA) granted orphan drug designation to AMX0035 for the treatment of amyotrophic lateral sclerosis (ALS), Amylyx Pharmaceuticals, the drug developer, announced in a press release. Orphan ... Read more

September 20, 2017

Cell Cleaning Mechanism Has Dual Role in ALS, Study Finds

News

A mechanism that cells normally use to keep them healthy was found to have a dual role in amyotrophic lateral sclerosis (ALS). While the process, called autophagy, delays disease progression ... Read more

August 28, 2017August 28, 2017

Wave Is Developing Two Drugs That Target a Common ALS Mutation

News

Wave Life Sciences is developing two ALS and frontotemporal dementia therapies that target a gene mutation common in both. The therapies target mutations of the C9orf72 gene, Wave said in ... Read more

July 7, 2017

Worldwide Clinical Trials Picked to Manage Phase 3 Study of NurOwn for ALS

News

Worldwide Clinical Trials was selected as the Clinical Research Organization (CRO) to run a Phase 3 study of the investigational stem-cell therapy NurOwn for the treatment of amyotrophic lateral sclerosis (ALS). BrainStorm Cell ... Read more

June 30, 2017June 30, 2017

Radicava and Its Swift FDA Approval Are Reasons for Hope, ALS Association Official Says

News

Radicava (edaravone), the first approved treatment for amyotrophic lateral sclerosis in 22 years, is being welcomed with “a great deal of excitement” in the ALS community, an ALS Association executive ... Read more

June 30, 2017June 30, 2017

Transcript of Interview with ALS Association’s Calaneet Balas on Radicava, the FDA, Insurance and Pricing

News

Below is a transcript of the ALS News Today interview with Calaneet Balas, executive vice president of strategy for the ALS Association. The nonprofit association, established in 1985, is active in promoting ... Read more

June 29, 2017June 29, 2017

Edaravone, Now Known as Radicava, Has Been ‘Minor Miracle’ for Some, ALS Worldwide Co-director Says

News

Edaravone — now more widely known by its U.S. brand name, Radicava — has produced “a minor miracle” for some amyotrophic lateral sclerosis patients, said Stephen Byer, co-director of ... Read more

June 16, 2017

Stem Cell Transplantation Shows Potential as ALS Therapy, Study Suggests

News

Stem cell transplantation in patients with amyotrophic lateral sclerosis (ALS) has the potential to be “an important alternative strategy” in treating the disease, a new study suggests. In recent decades, ... Read more

June 5, 2017June 5, 2017

Discovery of Molecular Trigger of Motor Neuron Death Could Aid ALS Treatment Research

News

Researchers have identified the sequence of molecular events leading to motor neuron death in amyotrophic lateral sclerosis (ALS), an important step forward that may lead to new therapies to halt this ... Read more