Posts by: Alice Melão

News

The final amyotrophic lateral sclerosis (ALS) patient treated with oral AMX0035 in the CENTAUR study has completed all scheduled follow-up visits and researchers will now evaluate data collected on the ... Read more

September 30, 2019October 2, 2019

Mitochondria Play a Critical Role in Neuroinflammation, Neuron Cell Death, Study Reveals

News

The release of fragmented or dysfunctional mitochondria — a cell’s powerhouse — by immune and structural cells inside the central nervous system is a critical step that triggers neuron ... Read more

September 26, 2019September 26, 2019

New Study Sheds Light on How Electrical Signals Control, Maintain Muscle Movement

News

A detailed analysis of the communication network between nerve and muscle cells in turtles has shed new light on how movement is controlled and maintained. These findings on how ... Read more

September 6, 2019September 11, 2019

Researchers Uncover HSP90 Mechanism That May Help Explain Motor Nerve Death

News

A new molecular mechanism that contributes to the death of some nerve cells has been discovered by a team of scientists led by researchers at Oregon State University. The ... Read more

August 7, 2019August 26, 2019

Underweight ALS Patients at Risk for Poorer Outcomes at Later Stages of Disease, Study Suggests

News

Being underweight when they start supported feeding puts patients with amyotrophic lateral sclerosis (ALS) at risk for poor outcomes at later stages of the disease, an Italian study has ... Read more

August 5, 2019August 27, 2019

ALS Patients Have Impaired Connectivity in Certain Brain Regions, Study Suggests

News

Amyotrophic lateral sclerosis (ALS) is characterized by specific changes in brain activity and connectivity, which are associated with motor and cognitive symptoms, an international research team has found. Therefore, ... Read more

July 16, 2019August 8, 2019

Enrollment Completed for Phase 3 REFALS Trial Evaluating Levosimendan in ALS Patients

News

The Phase 3 REFALS trial exploring the impact of oral levosimendan (ODM-109) in patients with amyotrophic lateral sclerosis (ALS) has completed its target enrollment, the therapy’s manufacturer, Orion, announced. ... Read more

June 21, 2019June 21, 2019

Multidisciplinary Care Linked to Increased Survival, Spanish Study Shows

News

Multidisciplinary care with timely use of respiratory and feeding support contributes to increased survival for people with amyotrophic lateral sclerosis (ALS), a single-center study in Spain finds. The study, ... Read more

June 20, 2019June 20, 2019

Vitamin D Supplements Cannot Prevent Motor Function Decline in ALS Patients, Study Suggests

News

Vitamin D supplementation can help overcome low levels of the vitamin often detected in people with amyotrophic lateral sclerosis (ALS). Still, such an alternative therapeutic approach has no meaningful ... Read more

June 7, 2019June 7, 2019

MediciNova Launches Phase 2b/3 Trial of Ibudilast for ALS

News

MediciNova has launched the Phase 2b/3 clinical trial that will explore the potential of ibudilast (MN-166) in patients with amyotrophic lateral sclerosis (ALS). Pending the success of the trial, ... Read more

Posts by: Alice Melão

Alice Melão

CENTAUR Phase 2 Trial of AMX0035, Potential ALS Treatment, Finishes Collecting Data

Mitochondria Play a Critical Role in Neuroinflammation, Neuron Cell Death, Study Reveals

New Study Sheds Light on How Electrical Signals Control, Maintain Muscle Movement

Researchers Uncover HSP90 Mechanism That May Help Explain Motor Nerve Death

Underweight ALS Patients at Risk for Poorer Outcomes at Later Stages of Disease, Study Suggests

ALS Patients Have Impaired Connectivity in Certain Brain Regions, Study Suggests

Enrollment Completed for Phase 3 REFALS Trial Evaluating Levosimendan in ALS Patients

Multidisciplinary Care Linked to Increased Survival, Spanish Study Shows

Vitamin D Supplements Cannot Prevent Motor Function Decline in ALS Patients, Study Suggests

MediciNova Launches Phase 2b/3 Trial of Ibudilast for ALS

Pin It on Pinterest