Posts by: Alice Melão

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A university-led clinical trial will assess the therapeutic effect of Celestone (betamethasone) injections in amyotrophic lateral sclerosis (ALS) patients with mutations in the FUS gene — a particular genetic type ... Read more

June 12, 2018June 12, 2018

Changes in Brain Structure, Blood Flow Linked to Varying Cognitive Deficits in ALS

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Cognitive deficits associated with amyotrophic lateral sclerosis (ALS) are linked to a particular pattern of abnormal changes and altered blood flow in specific brain regions, a study shows. The ... Read more

June 7, 2018June 7, 2018

Infusing Treg Immune Cells Has Potential to Slow ALS, Small Study Suggests

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Results from a Phase 1 clinical trial reveal that giving patients infusions of a specialized immune cell may be a viable option to safely slow the progression of amyotrophic ... Read more

June 1, 2018June 1, 2018

Two Enzymes Play Key Role Against Stress Granules in ALS, Other Neurological Disorders, Study Finds

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Two enzymes called USP5 and USP13 were found to have an important role in fighting back against toxic “stress granules,” a study reports. The study, titled “Deubiquitylases USP5 and ... Read more

May 22, 2018May 22, 2018

New Mouse Model Reveals Process Involved in Neuroinflammation in ALS, Other Disorders

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A new mouse model developed by researchers at Karolinska Institute in Sweden revealed a molecular mechanism that may contribute to the development of neurodegenerative diseases such as amyotrophic lateral ... Read more

May 21, 2018May 21, 2018

Protein That Helps to Regulate Innate Immune System Seen to Slow ALS Progression in Early Study in Mice

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The protein TRIF can prevent resident immune cells of the brain from activating abnormally and slow the progression of amyotrophic lateral sclerosis (ALS), researchers in Japan working in a mouse model ... Read more

May 11, 2018May 11, 2018

MIT Researchers Find Potential Role of C9orf72 Gene in ALS, Frontotemporal Dementia

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Mutations in the C9orf72 gene deregulate the process by which cells remove waste, leading to a buildup of toxic elements inside them, researchers have found. This discovery expands knowledge ... Read more

April 17, 2018April 17, 2018

#AAN2018 — NurOwn’s Beneficial Effect in ALS Sustained by miRNA Regulation, Study Suggests

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NurOwn, a cell therapy being developed by Brainstorm Cell Therapeutics, is able to maintain its therapeutic effects by significantly regulating the levels of a type of small RNA molecule linked to amyotrophic ... Read more

April 10, 2018April 10, 2018

Rilutek Prolongs Survival of ALS Patients in Later Stages, Study Shows

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Rilutek (riluzole) extends survival of patients with amyotrophic lateral sclerosis (ALS) who are at advanced stages of the disease, rather than preventing disease progression is early stages. Those findings ... Read more

March 26, 2018March 26, 2018

Mutations in KIF5A Gene Linked to ALS in Large-Scale International Study

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Newly identified mutations in the KIF5A gene were recently found to contribute to amyotrophic lateral sclerosis (ALS), the result of a large-scale collaborative study involving more than 250 researchers from ... Read more

Posts by: Alice Melão

Alice Melão

Kentucky Study Looking to Treat Genetic Form of ALS with Clusters in Appalachia

Changes in Brain Structure, Blood Flow Linked to Varying Cognitive Deficits in ALS

Infusing Treg Immune Cells Has Potential to Slow ALS, Small Study Suggests

Two Enzymes Play Key Role Against Stress Granules in ALS, Other Neurological Disorders, Study Finds

New Mouse Model Reveals Process Involved in Neuroinflammation in ALS, Other Disorders

Protein That Helps to Regulate Innate Immune System Seen to Slow ALS Progression in Early Study in Mice

MIT Researchers Find Potential Role of C9orf72 Gene in ALS, Frontotemporal Dementia

#AAN2018 — NurOwn’s Beneficial Effect in ALS Sustained by miRNA Regulation, Study Suggests

Rilutek Prolongs Survival of ALS Patients in Later Stages, Study Shows

Mutations in KIF5A Gene Linked to ALS in Large-Scale International Study

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