Posts by: Alice Melão

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Being underweight when they start supported feeding puts patients with amyotrophic lateral sclerosis (ALS) at risk for poor outcomes at later stages of the disease, an Italian study has ... Read more

August 5, 2019August 5, 2019

ALS Patients Have Impaired Connectivity in Certain Brain Regions, Study Suggests

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Amyotrophic lateral sclerosis (ALS) is characterized by specific changes in brain activity and connectivity, which are associated with motor and cognitive symptoms, an international research team has found. Therefore, ... Read more

July 16, 2019August 8, 2019

Enrollment Completed for Phase 3 REFALS Trial Evaluating Levosimendan in ALS Patients

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The Phase 3 REFALS trial exploring the impact of oral levosimendan (ODM-109) in patients with amyotrophic lateral sclerosis (ALS) has completed its target enrollment, the therapy’s manufacturer, Orion, announced. ... Read more

June 21, 2019June 21, 2019

Multidisciplinary Care Linked to Increased Survival, Spanish Study Shows

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Multidisciplinary care with timely use of respiratory and feeding support contributes to increased survival for people with amyotrophic lateral sclerosis (ALS), a single-center study in Spain finds. The study, ... Read more

June 20, 2019June 20, 2019

Vitamin D Supplements Cannot Prevent Motor Function Decline in ALS Patients, Study Suggests

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Vitamin D supplementation can help overcome low levels of the vitamin often detected in people with amyotrophic lateral sclerosis (ALS). Still, such an alternative therapeutic approach has no meaningful ... Read more

June 7, 2019June 7, 2019

MediciNova Launches Phase 2b/3 Trial of Ibudilast for ALS

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MediciNova has launched the Phase 2b/3 clinical trial that will explore the potential of ibudilast (MN-166) in patients with amyotrophic lateral sclerosis (ALS). Pending the success of the trial, ... Read more

June 5, 2019June 5, 2019

Electronic App to Monitor Dietary Intake May Benefit ALS Patients, Trial Data Suggest

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A diet monitoring app can help amyotrophic lateral sclerosis (ALS) patients to manage their calorie intake in order to maintain or even improve their weight, and achieve better outcomes, ... Read more

April 17, 2019June 3, 2019

FDA Approves Pivotal Phase 2b/3 Trial for Ibudilast in ALS Patients

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The U.S. Food and Drug Administration approved MediciNova’s plans for a pivotal Phase 2b/3 clinical trial that will explore the potential of ibudilast (MN-166) in patients with amyotrophic lateral ... Read more

April 2, 2019June 3, 2019

Improving Oxygen Supply to the Spinal Cord May Help Prevent ALS Progression, Mouse Study Suggests

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Increasing blood flow in the spinal cord by injecting a long-acting vasodilator can help prevent the progression of amyotrophic lateral sclerosis (ALS) in mice, a study shows. The study, ... Read more

March 27, 2019March 27, 2019

Zebrafish May Be Useful Experimental Model to Study ALS Associated with Angiogenin Mutations, Study Shows

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Widely used to study several human diseases, zebrafish can now be a useful preclinical model to study amyotrophic lateral sclerosis (ALS) linked to angiogenin mutations, according to researchers at ... Read more

Posts by: Alice Melão

Alice Melão

Underweight ALS Patients at Risk for Poorer Outcomes at Later Stages of Disease, Study Suggests

ALS Patients Have Impaired Connectivity in Certain Brain Regions, Study Suggests

Enrollment Completed for Phase 3 REFALS Trial Evaluating Levosimendan in ALS Patients

Multidisciplinary Care Linked to Increased Survival, Spanish Study Shows

Vitamin D Supplements Cannot Prevent Motor Function Decline in ALS Patients, Study Suggests

MediciNova Launches Phase 2b/3 Trial of Ibudilast for ALS

Electronic App to Monitor Dietary Intake May Benefit ALS Patients, Trial Data Suggest

FDA Approves Pivotal Phase 2b/3 Trial for Ibudilast in ALS Patients

Improving Oxygen Supply to the Spinal Cord May Help Prevent ALS Progression, Mouse Study Suggests

Zebrafish May Be Useful Experimental Model to Study ALS Associated with Angiogenin Mutations, Study Shows

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