Posts by: Alice Melão

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The U.S. Food and Drug Administration approved MediciNova’s plans for a pivotal Phase 2b/3 clinical trial that will explore the potential of ibudilast (MN-166) in patients with amyotrophic lateral ... Read more

April 2, 2019April 2, 2019

Improving Oxygen Supply to the Spinal Cord May Help Prevent ALS Progression, Mouse Study Suggests

News

Increasing blood flow in the spinal cord by injecting a long-acting vasodilator can help prevent the progression of amyotrophic lateral sclerosis (ALS) in mice, a study shows. The study, ... Read more

March 27, 2019March 27, 2019

Zebrafish May Be Useful Experimental Model to Study ALS Associated with Angiogenin Mutations, Study Shows

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Widely used to study several human diseases, zebrafish can now be a useful preclinical model to study amyotrophic lateral sclerosis (ALS) linked to angiogenin mutations, according to researchers at ... Read more

March 12, 2019March 12, 2019

Stem Cell Therapy Can Improve Survival, Motor Function of Mice with SOD1 Mutation, Study Shows

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Stem cell therapy using a certain type of stem cell called human mesenchymal stromal cells (hMSCs) may have the potential to improve outcomes and prevent progression of familial amyotrophic ... Read more

March 7, 2019March 7, 2019

Newly Identified GLT8D1 Genetic Variants Linked to Familial ALS, Study Reveals

News

New genetic mutations in the coding sequence of the GLT8D1 enzyme have been identified and linked to inherited amyotrophic lateral sclerosis (ALS), a study reports. Researchers at the University of ... Read more

February 28, 2019February 28, 2019

New Strategy May Prevent Toxic Protein Aggregates Linked to Neurodegenerative Disorders, Study Suggests

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A modified experimental version of the TDP-43 protein has revealed the underlying mechanisms that support its accumulation and the formation of toxic aggregates implicated in amyotrophic lateral sclerosis (ALS) ... Read more

February 25, 2019February 25, 2019

Nerve Injury May Trigger Onset, Progression of ALS Symptoms, Rat Study Suggests

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Small nerve injury may be the trigger for early manifestation or faster progression of amyotrophic lateral sclerosis (ALS) motor symptoms in the presence of disease-associated genetic contributing factors, a ... Read more

February 21, 2019February 21, 2019

Researchers Develop Predictive Platform for Personalized Care of ALS Patients

News

Researchers at Israel’s Ben-Gurion University (BGU) have developed an artificial intelligence (AI) platform that can help monitor and predict the course of amyotrophic lateral sclerosis (ALS). The tool was designed ... Read more

February 19, 2019February 19, 2019

Vps4 Protein Found to Protect Nerve Cells from Degeneration, Study Shows

News

Enhanced production of a protein called Vps4 was shown to delay the degenerative process in injured nerve cells, which may help researchers to better understand and treat nerve damage ... Read more

February 12, 2019February 12, 2019

Recumbent Stepper Safe, Feasible Exercise for ALS Patients, Study Suggests

News

Using a recumbent stepper is a safe and well-tolerated way for patients with amyotrophic lateral sclerosis (ALS) to do physical exercise, a pilot study suggests. The study, “Recumbent stepping ... Read more

Posts by: Alice Melão

Alice Melão

FDA Approves Pivotal Phase 2b/3 Trial for Ibudilast in ALS Patients

Improving Oxygen Supply to the Spinal Cord May Help Prevent ALS Progression, Mouse Study Suggests

Zebrafish May Be Useful Experimental Model to Study ALS Associated with Angiogenin Mutations, Study Shows

Stem Cell Therapy Can Improve Survival, Motor Function of Mice with SOD1 Mutation, Study Shows

Newly Identified GLT8D1 Genetic Variants Linked to Familial ALS, Study Reveals

New Strategy May Prevent Toxic Protein Aggregates Linked to Neurodegenerative Disorders, Study Suggests

Nerve Injury May Trigger Onset, Progression of ALS Symptoms, Rat Study Suggests

Researchers Develop Predictive Platform for Personalized Care of ALS Patients

Vps4 Protein Found to Protect Nerve Cells from Degeneration, Study Shows

Recumbent Stepper Safe, Feasible Exercise for ALS Patients, Study Suggests

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