Author Archives: Alice Melão

New Antibody Armanezumab May Be Possible Therapeutic Strategy for ALS

Researchers have developed an antibody, called armanezumab, which specifically targets defective tau protein. The molecule has potential for the treatment of amyotrophic lateral sclerosis (ALS), among other diseases. According to results of the study “Humanized monoclonal antibody armanezumab specific to N-terminus of pathological tau: characterization and therapeutic potency,”…

Potential Diagnostic Biomarkers for Amyotrophic Lateral Sclerosis Identified in Study

Recent research identified molecules in  the cerebrospinal fluid of people with amyotrophic lateral sclerosis,  particularly phosphorylated neurofilament heavy chain (pNfH), to be likely biomarkers for diagnosing ALS. ALS, an aggressive neurological disorder, is now diagnosed based on clinical evaluation. Biomarkers in the diagnostic process would allow clinicians to more easily distinguish ALS from…