Author Archives: Alice Melão

New Strategy May Prevent Toxic Protein Aggregates Linked to Neurodegenerative Disorders, Study Suggests

A modified experimental version of the TDP-43 protein has revealed the underlying mechanisms that support its accumulation and the formation of toxic aggregates implicated in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), a study reports. A detailed understanding of TDP-43-mediated neurotoxicity may help researchers find new targeted…

Researchers Develop Predictive Platform for Personalized Care of ALS Patients

Researchers at Israel’s Ben-Gurion University (BGU) have developed an artificial intelligence (AI) platform that can help monitor and predict the course of amyotrophic lateral sclerosis (ALS). The tool was designed by Boaz Lerne, PhD, associate professor at BGU, and his colleagues, in order to help identify biomarkers associated with neurodegenerative…

Researchers Move Closer to Giving Voice to Those Who Cannot Speak

A “new voice” for people who cannot verbally communicate, such as those living with amyotrophic lateral sclerosis (ALS) or recovering from stroke, is a step closer to becoming reality. Researchers from the Zuckerman Institute at Columbia University have developed a computer algorithm that can recognize a person’s thoughts as…

Nearly 60% of ALS Patients are Excluded from Clinical Trials, Stressing the Need for New Eligibility Criteria, Study Shows

The majority of patients with amyotrophic lateral sclerosis (ALS) are excluded from participating in clinical trials, a large study has revealed. This finding raises questions on the extrapolation of trial results for this patient population. The researchers also stressed the need for individualized risk-based criterion to balance the gains in…

Top 10 ALS Stories of 2018

ALS News Today brought you daily coverage of important discoveries, treatment developments, clinical trials, and other events dealing with amyotrophic lateral sclerosis (ALS) throughout 2018. As a reminder of what mattered most to you in 2018, here are the 10 most-read articles of last year with a brief description…