ALS Mouse Study Finds Favor in Muse Stem Cells
Injecting a specific type of stem cells into the bloodstream was able to reduce muscle shrinkage and promote motor neuron…
Articles by Joana Carvalho, PhD
I AM ALS ‘Playbook’ Aims to Foster Patient Advocacy Groups
I AM ALS, a nonprofit working for people affected by amyotrophic lateral sclerosis (ALS), is offering a guide to…
FDA, in Initial Review of NurOwn for ALS, Finds Data Lacking
Existing safety and effectiveness data from a Phase 3 clinical trial of NurOwn — an investigational cell-based therapy…
Moderate Physical Activity May Slow Muscle Deterioration
Moderate physical activity may slow muscle deterioration associated with the progression of amyotrophic lateral sclerosis (ALS), improving patients’ ability…
Mexiletine May Lessen Motor Neuron ‘Excitability’ to Ease Cramps, Small Trial Suggests
Mexiletine, a heart medication used off-label to treat muscle cramps due to amyotrophic lateral sclerosis (ALS), was found…
CNM-Au8 May Be Source of Motor Neuron Gains Being Seen in Phase 2 Trial
Nearly half of all patients in a Phase 2 trial of CNM-Au8, Clene Nanomedicine’s lead candidate for…
Extension Study Will Continue Evaluating Oral Edaravone
Mitsubishi Tanabe Pharma America (MTPA) has launched an extension study to assess the long-term effects of an investigational oral…
4th Potential ALS Therapy, SLS-005, Added to HEALEY Platform Trial
A Phase 2b/3 trial investigating the potential of SLS-005 (trehalose) to slow the progression of amyotrophic…
AstroRx Given at Higher Dose Still Safely Slowing ALS Progression, Trial Reports
A single infusion of AstroRx, an off-the-shelf, investigational cell therapy for amyotrophic lateral sclerosis (ALS),…
Gene Silencing Method Shows Promise to Treat Familial ALS Associated With SOD1 Mutations
A single dose of an artificial microRNA — a tiny RNA molecule that is able to control the activity…