Graphene May be Used to Detect Biomarkers for ALS, Study Reports
Graphene, a material made up of a thin sheet of carbon, may be used in the future to detect and…
Articles by Joana Carvalho, PhD
Bulbar-onset ALS in Patients 80 and Older May Lead to Shorter Survival, Study Reports
Bulbar-onset amyotrophic lateral sclerosis (ALS) is the most common form of the disease among patients 80 and older at…
Bulbar-onset ALS Diagnosed in Man with PNFA, Type of Frontotemporal Dementia
A man with progressive non-fluent aphasia (PNFA), one of the three types of frontotemporal dementia (FTD), was unusual in…
Combination of Imaging, Biomarkers Offers Better Assessment of ALS Patients, Study Finds
Combining structural brain imaging with molecular and clinical biomarkers allows for a detailed assessment of a patient’s clinical state, regardless…
Optimized Bi-PAP Protocol Improves ALS Patients’ Survival, Study Suggests
A new optimized protocol for the use of a noninvasive ventilation technique called bi-level positive airway pressure (Bi-PAP) allows patients…
Repair Cells Change in Neurodegenerative Disorders, Promoting Muscle Wasting and Scarring, Study Says
Cells that normally help to repair injured muscle tissue — called fibro-adipogenic progenitors — become key players in the muscle wasting…
Axon Loss in ALS Doesn’t Appear Linked to Death-promoting Molecule, Study in Mice Reports
Events leading to the loss of nerve cell fibers called axons appear to take place independent of Sarm1, a molecule known…
TDP-43 Accumulation Causes RNA Instability in Nerve Cells of ALS Patients
The accumulation of TDP-43, a widely expressed nuclear protein that binds both DNA and RNA, causes RNA instability in nerve…
Boosting Protein with Role in Getting Nutrients to Cells Prevented Muscle Wasting in ALS Mice, Study Finds
Restoring or artificially raising levels of a protein found in the spinal cord, mitofusin 2, Â worked to prevent nerve degeneration,…