Higher Risk of Pressure Sores in ALS Patients; Women, Young More Vulnerable, Study Finds
Patients with amyotrophic lateral sclerosis (ALS)Â are at increased risk for having pressure sores (PrS), according to a recent…
Articles by José Lopes, PhD
Specific RNA Alterations Key in ALS, Study Suggests
Specific alterations in RNA processing are molecular hallmarks of familial and sporadic forms of amyotrophic lateral sclerosis (ALS), a…
Insights from New System May Help Improve Speech Impairment in ALS, Other Disorders, Study Reports
A new portable system provides insights into the altered tongue, lip, and jaw motion in amyotrohic lateral sclerosis (ALS)…
Treeway’s Oral Formulation of Edavarone for ALS Shows Promise in Phase 1 Trial
An experimental oral formulation of edavorone for amyotrophic lateral sclerosis (ALS), called TW001, demonstrated promising pharmacological and safety…
Processes Driving FUS Proteins to Clump in ALS and Common Dementia Described in Study
The distinct processes that drive FUS proteins to aggregate and clump in both amyotrophic lateral sclerosis (ALS) and frontotemporal…
Worldwide Partners with Datavant to Improve Clinical Trials in ALS, Other Diseases
Worldwide Clinical Trials and the healthcare technology company Datavant are partnering in an effort to improve trials in neurological…
Alnylam Testing New Molecular Therapy Candidates for ALS, Other Neurodegenerative Diseases
Newly developed molecular treatment candidates called small interfering RNAs (siRNAs) have been successfully delivered to the brain and spinal cord…
Hypermetabolism in ALS Linked to Greater Functional Decline and Shorter Survival, Study Says
Patients with amyotrophic lateral sclerosis (ALS) show high prevalence of hypermetabolism, which leads to more rapid physical decline and…
#AAN2018 — ALS Treatment Candidate MN-166 Delays Disease Worsening, Improves Survival, Trial Shows
MediciNova’s investigational therapy MN-166 (ibudilast) was able to delay disease worsening and improve survival in amyotrophic lateral…
#AAN2018 – New Molecular Therapies May Be Treatment Strategy for ALS, Study Suggests
New antisense oligonucleotide (ASO) molecular therapies targeting the most common gene mutation in amyotrophic lateral sclerosis (ALS) and frontotemporal…