Ibudilast May Help Only Bulbar-Onset Patients, Early Analysis of Phase 2 Data Suggests
More amyotrophic lateral sclerosis (ALS) patients survived among those who completed a Phase 2 trial of MediciNova’s Ibudilast (MN-166),…
Articles by Magdalena Kegel
Stabilizing Motor Neuron Survival Protein Might Lead to New ALS Treatments, Harvard Researchers Find
A compound that stabilizes a protein crucial for the survival of motor neurons helped cells of amyotrophic lateral sclerosis (ALS) patients…
Study of ALS Protein Behavior Brings Researchers Closer to Finding New Treatments
Insights into the behavior of TDP-43 — a key protein in amyotrophic lateral sclerosis (ALS) development — may offer clues…
Inflammatory Marker Predicts ALS Disability and Survival, Supporting Development of Neuraltus Therapy NP001
Measuring blood levels of the inflammatory marker C-reactive protein (CRP) in patients with amyotrophic lateral sclerosis (ALS) can help physicians track…
Newly Discovered Mutation Caused ALS Case, Chinese Study Suggests
A previously unknown mutation in the BICD2 gene caused juvenile amyotrophic lateral sclerosis (ALS) in a Chinese woman in her…
ALS and Schizophrenia Come from Same Genetic Roots, Study Confirms
Schizophrenia in relatives of amyotrophic lateral sclerosis (ALS) patients is caused by shared genetic factors that increase the risk of…
Genetics Behind Cardiovascular Fitness May Increase ALS Risk, Study Reports
Amyotrophic lateral sclerosis (ALS) may be linked to genetic factors that promote cardiovascular fitness, according to a study indicating that…
Shapes of Protein Whose Mutations Are Linked to ALS May Offer Clues to Disease Progression
Researchers have mapped the possible changes in shape of a key amyotrophic lateral sclerosis (ALS) protein that becomes mutated, a development that…
Zontivity Might Increase ALS Risk, but Certainty Will Be Difficult to Prove
A cardiovascular medication called Zontivity (vorapaxar) may be linked to a slight, but still increased, risk of amyotrophic lateral sclerosis…
Pain in ALS Patients is Common but Not Studied Enough, Review Finds
People with amyotrophic lateral sclerosis (ALS) are frequently in pain, yet few studies focus on this aspect of the disease, according…