Researchers at the University of Tokyo demonstrated that the FDA-approved anti-epileptic drug perampanel is able to prevent the progression of amyotrophic lateral sclerosis (ALS) and normalize the death of motor neurons in an animal model of the disease. The findings indicate the drug may be a potential candidate for ALS treatment and…
Researchers at the University of California conducted a study on the molecular and genetic characteristics of two identical female twins, one only with amyotrophic lateral sclerosis (ALS), and found that environmental factors may be at the root of genetic modifications that cause the disease. The discovery may be a key to prevention…
Researchers at the University of Bari in Italy, tested an electronic nose to see if it could sniff out exhaled breath composition of amyotrophic lateral sclerosis (ALS) from healthy controls  – with the potential of the nose someday becoming a screening and diagnostic tool for the disease. The research paper, titled “…
Target ALS Foundation, focused on finding new treatments for amyotrophic lateral sclerosis (ALS), has selected RUCDR Infinite Biologics as the biorepository for banking and distributing the foundation’s human stem cell lines to be used in industry and research. The privately funded non-profit institution, funds consortia-based collaborative projects that aim to decrease obstacles…
A group of women in their 60s decided to go full Monty to raise awareness for amyotrophic lateral sclerosis (ALS). The idea came from lifelong friends of Wendy Rauwerdink of Sheboygan, Wisconsin, who had diagnosed with the disease. Her friends became engaged in the fight, always wanting to do more.
Amyotrophic lateral sclerosis (ALS) is commonly referred to as Lou Gehrig’s disease. But who was Lou Gehrig and how did his life impact awareness about the disease? Henry Louis Gehrig was born in New York, June 19, 1903, at a time when very few people were aware of ALS,…
Researchers at the Karolinska Institute in Sweden and the University of Barcelona in Spain studied the contribution of cellular redox environment changes to the stability and integrity of SOD1, a protein implicated in the development and progression of familial amyotrophic lateral sclerosis (ALS). A key finding was that mutations in the…
Researchers at the University of California-Riverside have shown, for the first time, that infection from the common parasite Toxoplasma gondii disrupts neurotransmitter glutamate function in the brain, potentially leading to neuronal death and neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS), in individuals predisposed to such conditions. The research paper, “…
Rapporteurs appointed by the European Medicines Agency (EMA) have recommended that AB Science SA’s combined treatment ‘masitinib with riluzole’ in the treatment of adults with amyotrophic lateral sclerosis (ALS) should be filed for conditional marketing authorization. AB Science specializes in developing and marketing protein kinase inhibitors (PKIs), a class of targeted proteins…
A multi-disciplinary team of researchers analyzed the genotype data of thousands of ALS patients, with the objective of identifying gene variants that influence survival in ALS. The genome-wide association study identified two novel loci that significantly influence patient survival. These key findings help researchers better understand the biology of the disease…
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